AIMC Topic: Nanoparticles
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Effect of laser photobiomodulation combined with hydroxyapatite nanoparticles on the osteogenic differentiation of mesenchymal stem cells using artificial intelligence: An in vitro study.
PloS one
Nov 14, 2024
AIM: To evaluate in vitro the effect of laser photobiomodulation (PBM) combined or not with 30-nm hydroxyapatite nanoparticles (HANp), on the osteogenic differentiation of human umbilical cord mesenchymal stem cells (hUC-MSCs) by morphometric analysi...
Exploring the cytotoxic and antioxidant properties of lanthanide-doped ZnO nanoparticles: a study with machine learning interpretation.
Journal of nanobiotechnology
Nov 10, 2024
BACKGROUND: Lanthanide-based nanomaterials offer a promising alternative for cancer therapy because of their selectivity and effectiveness, which can be modified and predicted by leveraging the improved accuracy and enhanced decision-making of machin...
Utilizing machine learning and molecular dynamics for enhanced drug delivery in nanoparticle systems.
Scientific reports
Nov 4, 2024
Materials data science and machine learning (ML) are pivotal in advancing cancer treatment strategies beyond traditional methods like chemotherapy. Nanotherapeutics, which merge nanotechnology with targeted drug delivery, exemplify this advancement b...
Optimising the production of PLGA nanoparticles by combining design of experiment and machine learning.
International journal of pharmaceutics
Nov 2, 2024
Poly(lactic-co-glycolic acid) (PLGA) is a widely used biodegradable polymer in drug delivery and nanoparticle (NP) formulation due to its controlled drug release properties and safety profiles. Among the methods available for NP production, nanopreci...
PREPRINT Machine Learning for the Sensitivity Analysis of a Model of the Cellular Uptake of Nanoparticles for the Treatment of Cancer.
International journal for numerical methods in biomedical engineering
Oct 29, 2024
Experimental studies on the cellular uptake of nanoparticles (NPs), useful for the investigation of NP-based drug delivery systems, are often difficult to interpret due to the large number of parameters that can contribute to the phenomenon. It is th...
Optimizing lipid nanoparticles for fetal gene delivery in vitro, ex vivo, and aided with machine learning.
Journal of controlled release : official journal of the Controlled Release Society
Oct 28, 2024
There is a clinical need to develop lipid nanoparticles (LNPs) to deliver congenital therapies to the fetus during pregnancy. The aim of these therapies is to restore normal fetal development and prevent irreversible conditions after birth. As a firs...
Effects of the co-exposure of microplastic/nanoplastic and heavy metal on plants: Using CiteSpace, meta-analysis, and machine learning.
Ecotoxicology and environmental safety
Oct 23, 2024
Micro/nanoplastics (MNPs) and heavy metals (HMs) coexist worldwide. Existing studies have reported different or even contradictory toxic effects of co-exposure to MNPs and HMs on plants, which may be related to various influencing factors. In this st...
Designing nanotheranostics with machine learning.
Nature nanotechnology
Oct 3, 2024
The inherent limits of traditional diagnoses and therapies have driven the development and application of emerging nanotechnologies for more effective and safer management of diseases, herein referred to as 'nanotheranostics'. Although many important...
Review of machine learning for lipid nanoparticle formulation and process development.
Journal of pharmaceutical sciences
Sep 27, 2024
Lipid nanoparticles (LNPs) are a subset of pharmaceutical nanoparticulate formulations designed to encapsulate, stabilize, and deliver nucleic acid cargoes in vivo. Applications for LNPs include new interventions for genetic disorders, novel classes ...
Machine learning- a new paradigm in nanoparticle-mediated drug delivery to cancerous tissues through the human cardiovascular system enhanced by magnetic field.
Scientific reports
Sep 27, 2024
Nanoparticle-mediated drug delivery offers a promising approach to targeted cancer therapy, leveraging the ability of nanoparticles to deliver therapeutic agents directly to cancerous tissues with minimal impact on surrounding healthy cells. The pres...
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