AIMC Topic: Neoplasms

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Peak learning of mass spectrometry imaging data using artificial neural networks.

Nature communications
Mass spectrometry imaging (MSI) is an emerging technology that holds potential for improving, biomarker discovery, metabolomics research, pharmaceutical applications and clinical diagnosis. Despite many solutions being developed, the large data size ...

T Cell Epitope Prediction and Its Application to Immunotherapy.

Frontiers in immunology
T cells play a crucial role in controlling and driving the immune response with their ability to discriminate peptides derived from healthy as well as pathogenic proteins. In this review, we focus on the currently available computational tools for ep...

Predicting the risk of cancer in adults using supervised machine learning: a scoping review.

BMJ open
OBJECTIVES: The purpose of this scoping review is to: (1) identify existing supervised machine learning (ML) approaches on the prediction of cancer in asymptomatic adults; (2) to compare the performance of ML models with each other and (3) to identif...

Artificial intelligence for solid tumour diagnosis in digital pathology.

British journal of pharmacology
Tumour diagnosis relies on the visual examination of histological slides by pathologists through a microscope eyepiece. Digital pathology, the digitalization of histological slides at high magnification with slides scanners, has raised the opportunit...

Precise Control of Customized Macrophage Cell Robot for Targeted Therapy of Solid Tumors with Minimal Invasion.

Small (Weinheim an der Bergstrasse, Germany)
Injecting micro/nanorobots into the body to kill tumors is one of the ultimate ambitions for medical nanotechnology. However, injecting current micro/nanorobots based on 3D-printed biocompatible materials directly into blood vessels for targeted ther...

SWnet: a deep learning model for drug response prediction from cancer genomic signatures and compound chemical structures.

BMC bioinformatics
BACKGROUND: One of the major challenges in precision medicine is accurate prediction of individual patient's response to drugs. A great number of computational methods have been developed to predict compounds activity using genomic profiles or chemic...

Predicting drug sensitivity of cancer cells based on DNA methylation levels.

PloS one
Cancer cell lines, which are cell cultures derived from tumor samples, represent one of the least expensive and most studied preclinical models for drug development. Accurately predicting drug responses for a given cell line based on molecular featur...

Deep learning models for benign and malign ocular tumor growth estimation.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing algorithm f...

Accurate and Feasible Deep Learning Based Semi-Automatic Segmentation in CT for Radiomics Analysis in Pancreatic Neuroendocrine Neoplasms.

IEEE journal of biomedical and health informatics
Current clinical practice or radiomics studies of pancreatic neuroendocrine neoplasms (pNENs) require manual delineation of the lesions in computed tomography (CT) images, which is time-consuming and subjective. We used a semi-automatic deep learning...