AIMC Topic: Neoplasms

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Design and application of tumor prediction model based on statistical method.

Computer assisted surgery (Abingdon, England)
Two prediction models for tumor prediction based on logistic regression and BP neural network were proposed in this paper; a sensitivity analysis of risk factors was also conducted. The two protocols will be implemented in the R language and demonstr...

Application of Deep Learning in Automated Analysis of Molecular Images in Cancer: A Survey.

Contrast media & molecular imaging
Molecular imaging enables the visualization and quantitative analysis of the alterations of biological procedures at molecular and/or cellular level, which is of great significance for early detection of cancer. In recent years, deep leaning has been...

Feature selection method based on support vector machine and shape analysis for high-throughput medical data.

Computers in biology and medicine
Proteomics data analysis based on the mass-spectrometry technique can provide a powerful tool for early diagnosis of tumors and other diseases. It can be used for exploring the features that reflect the difference between samples from high-throughput...

A new semi-supervised learning model combined with Cox and SP-AFT models in cancer survival analysis.

Scientific reports
Gene selection is an attractive and important task in cancer survival analysis. Most existing supervised learning methods can only use the labeled biological data, while the censored data (weakly labeled data) far more than the labeled data are ignor...

Reconstructing cancer drug response networks using multitask learning.

BMC systems biology
BACKGROUND: Translating in vitro results to clinical tests is a major challenge in systems biology. Here we present a new Multi-Task learning framework which integrates thousands of cell line expression experiments to reconstruct drug specific respon...

Using machine learning algorithms to identify genes essential for cell survival.

BMC bioinformatics
BACKGROUND: With the explosion of data comes a proportional opportunity to identify novel knowledge with the potential for application in targeted therapies. In spite of this huge amounts of data, the solutions to treating complex disease is elusive....

Predicting activities of daily living for cancer patients using an ontology-guided machine learning methodology.

Journal of biomedical semantics
BACKGROUND: Bio-ontologies are becoming increasingly important in knowledge representation and in the machine learning (ML) fields. This paper presents a ML approach that incorporates bio-ontologies and its application to the SEER-MHOS dataset to dis...

Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models.

Scientific reports
Translating the vast data generated by genomic platforms into accurate predictions of clinical outcomes is a fundamental challenge in genomic medicine. Many prediction methods face limitations in learning from the high-dimensional profiles generated ...

A deep learning-based multi-model ensemble method for cancer prediction.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Cancer is a complex worldwide health problem associated with high mortality. With the rapid development of the high-throughput sequencing technology and the application of various machine learning methods that have emerged i...

Sensor, Signal, and Imaging Informatics.

Yearbook of medical informatics
To summarize significant contributions to sensor, signal, and imaging informatics published in 2016. We conducted an extensive search using PubMed® and Web of Science® to identify the scientific contributions published in 2016 that addressed sensor...