Biochimica et biophysica acta. Molecular basis of disease
Apr 9, 2025
Despite advances in cancer diagnosis and treatment, the disease remains a major health challenge. Integrating multi-omics, radiomics, and artificial intelligence has improved detection, prognosis, and treatment monitoring. Molecular multi-omics provi...
This work aims to develop and investigate the feasibility of a hybrid model combining Monte Carlo (MC) simulations and deep learning (DL) to predict electronic portal imaging device (EPID) images based on MC-generated exit phase space energy fluence ...
Biomechanics and modeling in mechanobiology
Apr 8, 2025
This paper presents a mathematical and numerical framework for modelling and parametrising tumour evolution dynamics to enhance computer-aided diagnosis and personalised treatment. The model comprises six differential equations describing cancer cell...
OBJECTIVES: To summarize significant research contributions on cancer informatics published in 2023, an extensive search using PubMed/MEDLINE was conducted to identify the scientific contributions published in 2023 that address topics in cancer. The ...
OBJECTIVES: The emergence of large language models has resulted in a significant shift in informatics research and carries promise in clinical cancer care. Here we provide a narrative review of the recent use of large language models (LLMs) to suppor...
BACKGROUND: Cancer survivors and their caregivers, particularly those from disadvantaged backgrounds with limited health literacy or racial and ethnic minorities facing language barriers, are at a disproportionately higher risk of experiencing sympto...
Hyperthermia (HT) in combination with radio- and/or chemotherapy has become an accepted cancer treatment for distinct solid tumour entities. In HT, tumour tissue is exogenously heated to temperatures between 39 and 43 °C for 60 min. Temperature monit...
The precise identification of tumor T-cell antigens (TTCAs) is crucial for advancements in cancer immunotherapy and other clinical uses. In contrast to the labor-intensive and time-consuming process of experimentally identifying TTCAs, computational ...
Cell communication and signaling : CCS
Apr 5, 2025
BACKGROUND: Lysyl oxidases (LOX/LOXL1-4) are crucial for cancer progression, yet their transcriptional regulation, potential therapeutic targeting, prognostic value and involvement in immune regulation remain poorly understood. This study comprehensi...
International journal of computer assisted radiology and surgery
Apr 4, 2025
PURPOSE: Accurately classifying tissue margins during cancer surgeries is crucial for ensuring complete tumor removal. Rapid Evaporative Ionization Mass Spectrometry (REIMS), a tool for real-time intraoperative margin assessment, generates spectra th...
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