AIMC Topic: Neovascularization, Physiologic

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Myricitrin inhibits vascular endothelial growth factor-induced angiogenesis of human umbilical vein endothelial cells and mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Sep 17, 2020
In the present study, the protective effects of myricitrin against vascular endothelial growth factor (VEGF)-induced angiogenesis of vascular endothelial cells were characterized. Cells were induced with 50 ng/mL VEGF in the presence or absence of va...
Xenograft Model Antitumor Assays Cell Line, Tumor Biomarkers Mice Human Umbilical Vein Endothelial Cells Animals Angiogenesis Inhibitors Caspases Neovascularization, Physiologic Disease Models, Animal Apoptosis Vascular Endothelial Growth Factors Flavonoids Matrix Metalloproteinases Humans Neovascularization, Pathologic
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Simvastatin and nanofibrous poly(l-lactic acid) scaffolds to promote the odontogenic potential of dental pulp cells in an inflammatory environment.

Acta biomaterialia Dec 30, 2017
UNLABELLED: In this study, we investigated the anti-inflammatory, odontogenic and pro-angiogenic effects of integrating simvastatin and nanofibrous poly(l-lactic acid) (NF-PLLA) scaffolds on dental pulp cells (DPCs). Highly porous NF-PLLA scaffolds t...
Neovascularization, Physiologic Polyesters Alkaline Phosphatase Mesenchymal Stem Cells Simvastatin Cytoprotection Gene Expression Regulation Tissue Scaffolds Lipopolysaccharides Dental Pulp Cell Differentiation Human Umbilical Vein Endothelial Cells Inflammation Signal Transduction RNA, Messenger Odontogenesis Humans Nanofibers Biomarkers Young Adult
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Value of Bioinformatics Models for Predicting Translational Control of Angiogenesis.

Circulation research May 9, 2025
Angiogenesis, the formation of new blood vessels, is a fundamental biological process with implications for both physiological functions and pathological conditions. While the transcriptional regulation of angiogenesis, mediated by factors such as HI...
Animals Computational Biology Humans Protein Biosynthesis Angiogenesis Neovascularization, Pathologic Neovascularization, Physiologic
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Application of an artificial intelligence for quantitative analysis of endothelial capillary beds in vitro.

Clinical hemorheology and microcirculation Jan 1, 2024
BACKGROUND: The use of endothelial cell cultures has become fundamental to study angiogenesis. Recent advances in artificial intelligences (AI) offer opportunities to develop automated assessment methods in medical research, analyzing larger datasets...
Artificial Intelligence Neovascularization, Physiologic Coculture Techniques Capillaries Endothelial Cells Humans
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Investigating the anti-angiogenic effects of Fufang Kushen Injection in combination with cisplatin using a zebrafish model.

Pakistan journal of pharmaceutical sciences Sep 1, 2020
The Traditional Chinese Medicine formula Fufang Kushen Injection (FKI) has demonstrated potential to enhance the efficacy and reduce the toxicity of the chemotherapeutic drug cisplatin. However, there is insufficient evidence to determine whether the...
Dose-Response Relationship, Drug Zebrafish Proteins Drugs, Chinese Herbal Animals Cisplatin Angiogenesis Inhibitors Animals, Genetically Modified Neovascularization, Physiologic Zebrafish Drug Synergism Vascular Endothelial Growth Factor Receptor-2
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