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Classifying heterogeneous presentations of PTSD via the default mode, central executive, and salience networks with machine learning.

NeuroImage. Clinical
Intrinsic connectivity networks (ICNs), including the default mode network (DMN), the central executive network (CEN), and the salience network (SN) have been shown to be aberrant in patients with posttraumatic stress disorder (PTSD). The purpose of ...

Population coupling predicts the plasticity of stimulus responses in cortical circuits.

eLife
Some neurons have stimulus responses that are stable over days, whereas other neurons have highly plastic stimulus responses. Using a recurrent network model, we explore whether this could be due to an underlying diversity in their synaptic plasticit...

A double-hit of stress and low-grade inflammation on functional brain network mediates posttraumatic stress symptoms.

Nature communications
Growing evidence indicates a reciprocal relationship between low-grade systemic inflammation and stress exposure towards increased vulnerability to neuropsychiatric disorders, including posttraumatic stress disorder (PTSD). However, the neural correl...

Ensemble Deep Learning on Large, Mixed-Site fMRI Datasets in Autism and Other Tasks.

International journal of neural systems
Deep learning models for MRI classification face two recurring problems: they are typically limited by low sample size, and are abstracted by their own complexity (the "black box problem"). In this paper, we train a convolutional neural network (CNN)...

Discriminating stress from rest based on resting-state connectivity of the human brain: A supervised machine learning study.

Human brain mapping
Acute stress induces large-scale neural reorganization with relevance to stress-related psychopathology. Here, we applied a novel supervised machine learning method, combining the strengths of a priori theoretical insights with a data-driven approach...

Simulating Small Neural Circuits with a Discrete Computational Model.

Biological cybernetics
Simulations of neural activity are commonly based on differential equations. We address the question what can be achieved with a simplified discrete model. The proposed model resembles artificial neural networks enriched with additional biologically ...

Visual information flow in Wilson-Cowan networks.

Journal of neurophysiology
In this paper, we study the communication efficiency of a psychophysically tuned cascade of Wilson-Cowan and divisive normalization layers that simulate the retina-V1 pathway. This is the first analysis of Wilson-Cowan networks in terms of multivaria...

BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets.

Communications biology
Understanding how cognitive functions emerge from brain structure depends on quantifying how discrete regions are integrated within the broader cortical landscape. Recent work established that macroscale brain organization and function can be describ...

Efficient inverse graphics in biological face processing.

Science advances
Vision not only detects and recognizes objects, but performs rich inferences about the underlying scene structure that causes the patterns of light we see. Inverting generative models, or "analysis-by-synthesis", presents a possible solution, but its...

Pre-Synaptic Pool Modification (PSPM): A supervised learning procedure for recurrent spiking neural networks.

PloS one
Learning synaptic weights of spiking neural network (SNN) models that can reproduce target spike trains from provided neural firing data is a central problem in computational neuroscience and spike-based computing. The discovery of the optimal weight...