AIMC Topic: Ovarian Neoplasms

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Weakly supervised deep learning for prediction of treatment effectiveness on ovarian cancer from histopathology images.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Despite the progress made during the last two decades in the surgery and chemotherapy of ovarian cancer, more than 70 % of advanced patients are with recurrent cancer and decease. Surgical debulking of tumors following chemotherapy is the conventiona...

Application of artificial intelligence in the diagnosis and prognostic prediction of ovarian cancer.

Computers in biology and medicine
In recent years, the wide application of artificial intelligence (AI) has dramatically improved the work efficiency of clinicians and reduced their workload. This review provides a glance at the latest advances in AI-assisted diagnosis and prognostic...

A machine learning approach applied to gynecological ultrasound to predict progression-free survival in ovarian cancer patients.

Archives of gynecology and obstetrics
In a growing number of social and clinical scenarios, machine learning (ML) is emerging as a promising tool for implementing complex multi-parametric decision-making algorithms. Regarding ovarian cancer (OC), despite the standardization of features t...

Deep Learning Prediction of Ovarian Malignancy at US Compared with O-RADS and Expert Assessment.

Radiology
Background Deep learning (DL) algorithms could improve the classification of ovarian tumors assessed with multimodal US. Purpose To develop DL algorithms for the automated classification of benign versus malignant ovarian tumors assessed with US and ...

Glycosylation-Related Genes Predict the Prognosis and Immune Fraction of Ovarian Cancer Patients Based on Weighted Gene Coexpression Network Analysis (WGCNA) and Machine Learning.

Oxidative medicine and cellular longevity
BACKGROUND: Ovarian cancer (OC) is a malignancy exhibiting high mortality in female tumors. Glycosylation is a posttranslational modification of proteins but research has failed to demonstrate a systematic link between glycosylation-related signature...

Machine Learning analysis of high-grade serous ovarian cancer proteomic dataset reveals novel candidate biomarkers.

Scientific reports
Ovarian cancer is one of the most common gynecological malignancies, ranking third after cervical and uterine cancer. High-grade serous ovarian cancer (HGSOC) is one of the most aggressive subtype, and the late onset of its symptoms leads in most cas...

Stem-cell based, machine learning approach for optimizing natural killer cell-based personalized immunotherapy for high-grade ovarian cancer.

The FEBS journal
Advanced high-grade serous ovarian cancer continues to be a therapeutic challenge for those affected using the current therapeutic interventions. There is an increasing interest in personalized cancer immunotherapy using activated natural killer (NK)...

Artificial intelligence-based image analysis can predict outcome in high-grade serous carcinoma via histology alone.

Scientific reports
High-grade extrauterine serous carcinoma (HGSC) is an aggressive tumor with high rates of recurrence, frequent chemotherapy resistance, and overall 5-year survival of less than 50%. Beyond determining and confirming the diagnosis itself, pathologist ...

A machine learning approach to identify predictive molecular markers for cisplatin chemosensitivity following surgical resection in ovarian cancer.

Scientific reports
Ovarian cancer is associated with poor prognosis. Platinum resistance contributes significantly to the high rate of tumour recurrence. We aimed to identify a set of molecular markers for predicting platinum sensitivity. A signature predicting cisplat...

Semi-Supervised Topological Analysis for Elucidating Hidden Structures in High-Dimensional Transcriptome Datasets.

IEEE/ACM transactions on computational biology and bioinformatics
Topological data analysis (TDA) is a powerful method for reducing data dimensionality, mining underlying data relationships, and intuitively representing the data structure. The Mapper algorithm is one such tool that projects high-dimensional data to...