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Pancreatic Neoplasms

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Robust and consistent biomarker candidates identification by a machine learning approach applied to pancreatic ductal adenocarcinoma metastasis.

BMC medical informatics and decision making
BACKGROUND: Machine Learning (ML) plays a crucial role in biomedical research. Nevertheless, it still has limitations in data integration and irreproducibility. To address these challenges, robust methods are needed. Pancreatic ductal adenocarcinoma ...

Noninvasive prediction of lymph node metastasis in pancreatic cancer using an ultrasound-based clinicoradiomics machine learning model.

Biomedical engineering online
OBJECTIVES: This study was designed to explore and validate the value of different machine learning models based on ultrasound image-omics features in the preoperative diagnosis of lymph node metastasis in pancreatic cancer (PC).

A machine learning model based on clinical features and ultrasound radiomics features for pancreatic tumor classification.

Frontiers in endocrinology
OBJECTIVE: This study aimed to construct a machine learning model using clinical variables and ultrasound radiomics features for the prediction of the benign or malignant nature of pancreatic tumors.

Endoscopic ultrasonography-based intratumoral and peritumoral machine learning radiomics analyses for distinguishing insulinomas from non-functional pancreatic neuroendocrine tumors.

Frontiers in endocrinology
OBJECTIVES: To develop and validate radiomics models utilizing endoscopic ultrasonography (EUS) images to distinguish insulinomas from non-functional pancreatic neuroendocrine tumors (NF-PNETs).

OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data.

Cellular oncology (Dordrecht, Netherlands)
PURPOSE: Pancreatic Ductal Adenocarcinoma (PDAC) remains a challenging disease due to its complex biology and aggressive behavior with an urgent need for efficient therapeutic strategies. To assess therapy response, pre-clinical PDAC organoid-based m...

Preliminary study on the ability of the machine learning models based on F-FDG PET/CT to differentiate between mass-forming pancreatic lymphoma and pancreatic carcinoma.

European journal of radiology
PURPOSE: The objective of this study was to preliminarily assess the ability of metabolic parameters and radiomics derived from F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) to distinguish mass-forming pancreati...

Radiomics and deep learning models for CT pre-operative lymph node staging in pancreatic ductal adenocarcinoma: A systematic review and meta-analysis.

European journal of radiology
PURPOSE: To evaluate the diagnostic accuracy of computed tomography (CT)-based radiomic algorithms and deep learning models to preoperatively identify lymph node metastasis (LNM) in patients with pancreatic ductal adenocarcinoma (PDAC).

Machine Learning Models for Pancreatic Cancer Risk Prediction Using Electronic Health Record Data-A Systematic Review and Assessment.

The American journal of gastroenterology
INTRODUCTION: Accurate risk prediction can facilitate screening and early detection of pancreatic cancer (PC). We conducted a systematic review to critically evaluate effectiveness of machine learning (ML) and artificial intelligence (AI) techniques ...

Effect of chemotherapy on prognosis in patients with primary pancreatic signet ring cell carcinoma: A large real-world study based on machine learning.

PloS one
BACKGROUND: Primary pancreatic signet ring cell carcinoma (PSRCC), an extremely rare histologic variant of pancreatic cancer, has a poor prognosis. This study aimed to investigate the prognostic value of chemotherapy in PSRCC.

DenseNet model incorporating hybrid attention mechanisms and clinical features for pancreatic cystic tumor classification.

Journal of applied clinical medical physics
PURPOSE: The aim of this study is to develop a deep learning model capable of discriminating between pancreatic plasma cystic neoplasms (SCN) and mucinous cystic neoplasms (MCN) by leveraging patient-specific clinical features and imaging outcomes. T...