Parkinson's disease is a neurodegenerative disorder that is associated with aging, leading to the progressive deterioration of certain regions of the brain. Accurate and timely diagnosis plays a crucial role in facilitating optimal therapy and improv...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Mar 7, 2025
The last decade has witnessed a notable surge in deep learning applications for electroencephalography (EEG) data analysis, showing promising improvements over conventional statistical techniques. However, deep learning models can underperform if tra...
CPT: pharmacometrics & systems pharmacology
Mar 5, 2025
Approximately 15% of patients suspected of having Parkinson's disease (PD) present dopamine active transporter (DaT) scans without evidence of dopaminergic deficits (SWEDD), most of which will never develop PD. Leveraging Movement Disorders Society U...
BACKGROUND AND OBJECTIVE: Motor diagnosis, monitoring and management of Parkinson's disease (PD) focuses mainly on observational methods and, clinical scales, resulting in a subjective evaluation. Inertial sensors combined with artificial intelligenc...
OBJECTIVE: To develop and validate a deep neural network (DNN) model for diagnosing Parkinson's Disease (PD) using handwritten spiral and wave images, and to compare its performance with various machine learning (ML) and deep learning (DL) models.
Machine learning approaches including deep learning models have shown promising performance in the automatic detection of Parkinson's disease. These approaches rely on different types of data with voice recordings being the most used due to the conve...
Parkinson's Disease (PD) is a growing burden with varied clinical manifestations and responses to Subthalamic Nucleus Deep Brain Stimulation (STN-DBS). At present, there is no effective and simple machine learning model based on comprehensive clinica...
Accurate prediction of Parkinson's disease tremor (PDT) is crucial for developing assistive technologies; however, this is challenging due to the nonlinear, stochastic, and nonstationary characteristics of PDT, which substantially vary among patients...
European journal of nuclear medicine and molecular imaging
Feb 18, 2025
PURPOSE: Center-specific effects in PET brain scans arise due to differences in technical and procedural aspects. This restricts the merging of data between centers and introduces source-specific bias.
OBJECTIVE: Functional imaging using the dopamine transporter (DAT) as a biomarker has proven effective in assessing dopaminergic neuron degeneration in the striatum. In assessing the neuron degeneration, visual and semiquantitative methods are used t...
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