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Parkinsonian Disorders

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Deep Learning-Based Algorithm for Automatic Quantification of Nigrosome-1 and Parkinsonism Classification Using Susceptibility Map-Weighted MRI.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: The diagnostic performance of deep learning model that simultaneously detecting and quantifying nigrosome-1 abnormality by using susceptibility map-weighted imaging (SMwI) remains unexplored. This study aimed to develop and va...

Differential diagnosis of multiple system atrophy with predominant parkinsonism and Parkinson's disease using neural networks (part II).

Journal of the neurological sciences
Neural networks (NNs) possess the capability to learn complex data relationships, recognize inherent patterns by emulating human brain functions, and generate predictions based on novel data. We conducted deep learning utilizing an NN to differentiat...

Differentiating atypical parkinsonian syndromes with hyperbolic few-shot contrastive learning.

NeuroImage
Differences in iron accumulation patterns have been observed in susceptibility-weighted images across different classes of atypical parkinsonian syndromes (APS). Deep learning methods have shown great potential in automatically detecting these differ...

Video-Based Detection of Freezing of Gait in Daily Clinical Practice in Patients With Parkinsonism.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Freezing of gait (FoG) is a prevalent symptom among individuals with Parkinson's disease and related disorders. FoG detection from videos has been developed recently; however, the process requires using videos filmed within a controlled environment. ...

Motor assessment of X-linked dystonia parkinsonism via machine-learning-based analysis of wearable sensor data.

Scientific reports
X-linked dystonia parkinsonism (XDP) is a neurogenetic combined movement disorder involving both parkinsonism and dystonia. Complex, overlapping phenotypes result in difficulties in clinical rating scale assessment. We performed wearable sensor-based...

The role of AI and machine learning in the diagnosis of Parkinson's disease and atypical parkinsonisms.

Parkinsonism & related disorders
Parkinson's disease is a neurodegenerative movement disorder associated with motor and non-motor symptoms causing severe disability as the disease progresses. The development of biomarkers for Parkinson's disease to diagnose patients earlier and pred...

Deep learning regressor model based on nigrosome MRI in Parkinson syndrome effectively predicts striatal dopamine transporter-SPECT uptake.

Neuroradiology
PURPOSE: Nigrosome imaging using susceptibility-weighted imaging (SWI) and dopamine transporter imaging using I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)-nortropane (I-FP-CIT) single-photon emission computerized tomography (SPECT) can eval...