AIMC Topic: Phenotype

Clear Filters Showing 831 to 840 of 922 articles

Phenomapping Heart Failure with Preserved Ejection Fraction Using Machine Learning Cluster Analysis: Prognostic and Therapeutic Implications.

Heart failure clinics Jul 1, 2021
Heart failure with preserved ejection fraction (HFpEF) is characterized by a high rate of hospitalization and mortality (up to 84% at 5 years), which are similar to those observed for heart failure with reduced ejection fraction (HFrEF). These epidem...
Humans Machine Learning Stroke Volume Heart Failure Disease Management Phenotype Prognosis
View on PubMed DOI

Using graph convolutional neural networks to learn a representation for glycans.

Cell reports Jun 15, 2021
As the only nonlinear and the most diverse biological sequence, glycans offer substantial challenges for computational biology. These carbohydrates participate in nearly all biological processes-from protein folding to viral cell entry-yet are still ...
Viruses Models, Molecular Polysaccharides Phenotype Machine Learning Phylogeny Neural Networks, Computer
View on PubMed DOI

High-throughput image segmentation and machine learning approaches in the plant sciences across multiple scales.

Emerging topics in life sciences May 21, 2021
Agriculture has benefited greatly from the rise of big data and high-performance computing. The acquisition and analysis of data across biological scales have resulted in strategies modeling inter- actions between plant genotype and environment, mode...
Machine Learning Phenotype Plant Development Plants Stress, Physiological
View on PubMed DOI

Which image-based phenotypes are most promising for using AI to understand cellular functions and why?

Cell systems May 19, 2021
Artificial Intelligence Phenotype Cell Physiological Phenomena
View on PubMed DOI

Challenges for FAIR-compliant description and comparison of crop phenotype data with standardized controlled vocabularies.

Database : the journal of biological databases and curation May 15, 2021
Crop phenotypic data underpin many pre-breeding efforts to characterize variation within germplasm collections. Although there has been an increase in the global capacity for accumulating and comparing such data, a lack of consistency in the systemat...
Plant Breeding Biological Ontologies Vocabulary, Controlled Phenotype Metadata
View on PubMed DOI

Predicting candidate genes from phenotypes, functions and anatomical site of expression.

Bioinformatics (Oxford, England) May 5, 2021
MOTIVATION: Over the past years, many computational methods have been developed to incorporate information about phenotypes for disease-gene prioritization task. These methods generally compute the similarity between a patient's phenotypes and a data...
Machine Learning Software Biological Ontologies Mice Phenotype Data Management Animals
View on PubMed DOI

Application of deep learning methods in biological networks.

Briefings in bioinformatics Mar 22, 2021
The increase in biological data and the formation of various biomolecule interaction databases enable us to obtain diverse biological networks. These biological networks provide a wealth of raw materials for further understanding of biological system...
Microbiota Data Mining Proteins Drug Interactions Drug Delivery Systems Drug Discovery Protein Interaction Maps Deep Learning Humans Neural Networks, Computer Algorithms Genotype Phenotype
View on PubMed DOI

Categorization of birth weight phenotypes for inclusion in genetic evaluations using a deep neural network.

Journal of animal science Mar 1, 2021
Birth weight (BW) serves as a valuable indicator of the economically relevant trait of calving ease (CE), and erroneous data collection for BW could impact genetic evaluations for CE. The objective of the current study was to evaluate the use of deep...
Phenotype Animals Birth Weight Data Collection Models, Genetic Neural Networks, Computer Goals
View on PubMed DOI

The Human Phenotype Ontology in 2021.

Nucleic acids research Jan 8, 2021
The Human Phenotype Ontology (HPO, https://hpo.jax.org) was launched in 2008 to provide a comprehensive logical standard to describe and computationally analyze phenotypic abnormalities found in human disease. The HPO is now a worldwide standard for ...
Genome Pharmacogenetics Disease Genotype International Cooperation Biological Ontologies Humans Phenotype Computational Biology Software Infant, Newborn Neonatal Screening Databases, Factual Disease Models, Animal Animals Terminology as Topic Internet
View on PubMed DOI

Machine Learning to Identify Gene Interactions from High-Throughput Mutant Crosses.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2021
Advances in molecular genetics through high-throughput gene mutagenesis and genetic crossing have enabled gene interaction mapping across whole genomes. Detecting gene interactions in even small microbial genomes relies on measuring growth phenotypes...
Chromosome Mapping Genome Machine Learning Epistasis, Genetic Phenotype
View on PubMed DOI
Popular Topics
Recent Journals