AIMC Topic: Plant Extracts

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In vitro antimycobacterial activity of six Cameroonian medicinal plants using microplate alamarBlue assay.

International journal of mycobacteriology
OBJECTIVE/BACKGROUND: The latest incidence of tuberculosis (TB) (per 100,000 people) in Cameroon was 243.00 as of 2011. Over the past 21 years, the value for this indicator has fluctuated between 112.00 in 1990 and 320.00 in 2003. Worldwide, this inc...

Artificial neural network modelling of the antioxidant activity and phenolic compounds of bananas submitted to different drying treatments.

Food chemistry
Bananas (cv. Musa nana and Musa cavendishii) fresh and dried by hot air at 50 and 70°C and lyophilisation were analysed for phenolic contents and antioxidant activity. All samples were subject to six extractions (three with methanol followed by three...

Benchtop Vis-NIR spectroscopy meets machine learning for multi-task analysis in Hongmeiren citrus: Geographical origin identification and antioxidant component quantification.

Food chemistry
Due to geographical indication advantage of Hongmeiren (HMR) citrus, economically motivated origin fraud has emerged, alongside significant differences in antioxidant components. This study employed benchtop visible and near-infrared (Vis-NIR) spectr...

Intelligent transformation of ultrasound-assisted novel solvent extraction plant active ingredients: Tools for machine learning and deep learning.

Food chemistry
Ultrasound-assisted novel solvent extraction enhances plant bioactive compound yield via cavitation, mechanical, and thermal mechanisms. However, the high designability of novel solvents, the multiple influence factors for extracting results, the com...

Genetic Neural Network-Assisted Natural Deep Eutectic Solvent Extraction for Enhanced Bioactive Yield from Folium Mori with Cytotoxicity Profiling.

Journal of chromatographic science
Natural deep eutectic solvents (NaDESs) was efficient and green for componential extraction of traditional Chinese medicine compared to conventional organic solvents. In this study, a total of nine NaDESs were synthesized and screened, and Proline-Ur...

Revisiting In-Gas Transformations of Quinate Conjugates Through the LC-qTOF-MS and Molecular Networking Topology.

Rapid communications in mass spectrometry : RCM
RATIONALE: The emergence of computational metabolomics tools such as molecular networking and machine learning-based platforms like SIRIUS has significantly advanced MS-based metabolomics studies. These tools enable rapid metabolite identification by...

Tribulus terrestris L. Extract Alleviates Atherosclerosis by Suppressing TNF-α-Mediated Macrophage Inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Atherosclerosis (AS) is a major contributor to cardiovascular disease. In traditional Chinese medicine, Tribulus terrestris L., or Baijili (BJL), has shown therapeutic effects on inflammation and cardiovascular issues. Our prior research indicated th...

Computer-aided unveiling molecular mechanisms of Xylocarpus granatum against colorectal cancer: therapeutic intervention targeting P13K-AKT signaling pathway.

Computers in biology and medicine
Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality globally, with increasing incidence rates, particularly in early-onset cases. Despite advances in treatment, many developing countries face affordability and safety ...

Integrating machine learning and traditional methods for cadmium prediction and bioavailability assessment in Paeoniae Radix Alba: a case study from Bozhou, Anhui Province.

Environmental geochemistry and health
Soil heavy metal contamination, particularly cadmium (Cd), poses a significant risk to ecosystems and human health. This study investigates the distribution and bioavailability of Cd in soil and Paeoniae Radix Alba system from Qiaocheng District, Boz...