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Point-of-Care Systems

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Smartphone-based fluorescent lateral flow immunoassay platform for highly sensitive point-of-care detection of Zika virus nonstructural protein 1.

Analytica chimica acta
Simple, inexpensive, and rapid diagnostic tests in low-resource settings with limited laboratory equipment and technical expertise are instrumental in reducing morbidity and mortality from epidemic infectious diseases. We developed a smartphone-based...

Validation of the Behavior of a Knowledge Base Implementing Clinical Guidelines for Point-of-Care Antiretroviral Toxicity Monitoring.

AMIA ... Annual Symposium proceedings. AMIA Symposium
This study investigated the automated detection of antiretroviral toxicities in structured electronic health records data. The evaluation compared responses generated by 5 clinical pharmacists and 1 prototype knowledge-based application for 15 random...

Enhanced Point-of-Care Ultrasound Applications by Integrating Automated Feature-Learning Systems Using Deep Learning.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Recent applications of artificial intelligence (AI) and deep learning (DL) in health care include enhanced diagnostic imaging modalities to support clinical decisions and improve patients' outcomes. Focused on using automated DL-based systems to impr...

Deep Learning in Drug Discovery and Medicine; Scratching the Surface.

Molecules (Basel, Switzerland)
The practice of medicine is ever evolving. Diagnosing disease, which is often the first step in a cure, has seen a sea change from the discerning hands of the neighborhood physician to the use of sophisticated machines to use of information gleaned f...

Analytical Concordance of Diverse Point-of-Care and Central Laboratory Troponin I Assays.

The journal of applied laboratory medicine
BACKGROUND: Cardiac troponin I (cTnI) 99th percentile cutoffs, used in the diagnosis of acute myocardial infarction, are not standardized across cTnI assays. We compared 3 point-of-care (POC) and 1 central laboratory contemporary cTnI assays against ...

Computational Optics Enables Breast Cancer Profiling in Point-of-Care Settings.

ACS nano
The global burden of cancer, severe diagnostic bottlenecks in underserved regions, and underfunded health care systems are fueling the need for inexpensive, rapid, and treatment-informative diagnostics. On the basis of advances in computational optic...

A Comparative Study of Point-of-Care Prothrombin Time in Cardiopulmonary Bypass Surgery.

Journal of cardiothoracic and vascular anesthesia
OBJECTIVE: Point-of-care (POC) devices allow for prothrombin time/international normalized ratio (PT/INR) testing in whole blood (WB) and timely administration of plasma or prothrombin complex concentrate during cardiopulmonary bypass surgery. This s...

Knowledge as a Service at the Point of Care.

AMIA ... Annual Symposium proceedings. AMIA Symposium
An electronic health record (EHR) can assist the delivery of high-quality patient care, in part by providing the capability for a broad range of clinical decision support, including contextual references (e.g., Infobuttons), alerts and reminders, ord...