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Positron-Emission Tomography

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Multilevel Feature Representation of FDG-PET Brain Images for Diagnosing Alzheimer's Disease.

IEEE journal of biomedical and health informatics
Using a single imaging modality to diagnose Alzheimer's disease (AD) or mild cognitive impairment (MCI) is a challenging task. FluoroDeoxyGlucose Positron Emission Tomography (FDG-PET) is an important and effective modality used for that purpose. In ...

Global temporal lobe asymmetry as a semi-quantitative imaging biomarker for temporal lobe epilepsy lateralization: A machine learning classification study.

Hellenic journal of nuclear medicine
OBJECTIVE: The purpose of this study was to evaluate the utility of global semi-quantitative analysis via fluorine-18-flurodeoxyglucose positron emission tomography (F-FDG PET) at lateralizing seizure foci and diagnosing patients with unilateral temp...

Attenuation correction for brain PET imaging using deep neural network based on Dixon and ZTE MR images.

Physics in medicine and biology
Positron emission tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR hybrid sys...

Multicenter validation of [F]-FDG PET and support-vector machine discriminant analysis in automatically classifying patients with amyotrophic lateral sclerosis versus controls.

Amyotrophic lateral sclerosis & frontotemporal degeneration
OBJECTIVE: F-Fluorodeoxyglucose (F-FDG) positron emission tomography (PET) single-center studies using support vector machine (SVM) approach to differentiate amyotrophic lateral sclerosis (ALS) from controls have shown high overall accuracy on an ind...

Machine learning in the integration of simple variables for identifying patients with myocardial ischemia.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: A significant number of variables are obtained when characterizing patients suspected with myocardial ischemia or at risk of MACE. Guidelines typically use a handful of them to support further workup or therapeutic decisions. However, it ...

Adaptive template generation for amyloid PET using a deep learning approach.

Human brain mapping
Accurate spatial normalization (SN) of amyloid positron emission tomography (PET) images for Alzheimer's disease assessment without coregistered anatomical magnetic resonance imaging (MRI) of the same individual is technically challenging. In this st...

Identification of Alzheimer's disease and mild cognitive impairment using multimodal sparse hierarchical extreme learning machine.

Human brain mapping
Different modalities such as structural MRI, FDG-PET, and CSF have complementary information, which is likely to be very useful for diagnosis of AD and MCI. Therefore, it is possible to develop a more effective and accurate AD/MCI automatic diagnosis...

Enhancing the Image Quality via Transferred Deep Residual Learning of Coarse PET Sinograms.

IEEE transactions on medical imaging
Increasing the image quality of positron emission tomography (PET) is an essential topic in the PET community. For instance, thin-pixelated crystals have been used to provide high spatial resolution images but at the cost of sensitivity and manufactu...

Multiscale deep neural network based analysis of FDG-PET images for the early diagnosis of Alzheimer's disease.

Medical image analysis
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases with a commonly seen prodromal mild cognitive impairment (MCI) phase where memory loss is the main complaint progressively worsening with behavior issues and poor self-care...

Using convolutional neural networks to estimate time-of-flight from PET detector waveforms.

Physics in medicine and biology
Although there have been impressive strides in detector development for time-of-flight positron emission tomography, most detectors still make use of simple signal processing methods to extract the time-of-flight information from the detector signals...