MOTIVATION: Personalized cancer treatments require accurate drug response predictions. Existing deep learning methods show promise but higher accuracy is needed to serve the purpose of precision medicine. The prediction accuracy can be improved with ...
Acta orthopaedica et traumatologica turcica
Mar 1, 2024
To achieve meaningful, patient-centered outcomes following adult spinal deformity (ASD) surgery, it is crucial to engage in precise preoperative planning, perform excellent intraoperative execution, and ensure careful postoperative management. The fi...
MOTIVATION: Classification of samples using biomedical omics data is a widely used method in biomedical research. However, these datasets often possess challenging characteristics, including high dimensionality, limited sample sizes, and inherent bia...
Frontiers in bioscience (Landmark edition)
Jan 12, 2024
Advances in gene sequencing technology and decreasing costs have resulted in a proliferation of genomic data as an integral component of big data. The availability of vast amounts of genomic data and more sophisticated genomic analysis techniques has...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 1, 2024
This study introduces a groundbreaking approach to early cancer detection through the analysis of cell-free DNA (cfDNA), utilizing machine learning algorithms to navigate the complexities of low circulating tumor DNA (ctDNA) fractions and genetic het...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 1, 2024
Many data resources generate, process, store, or provide kidney related molecular, pathological, and clinical data. Reference ontologies offer an opportunity to support knowledge and data integration. The Kidney Precision Medicine Project (KPMP) team...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 1, 2024
The delivery of effective targeted therapies requires comprehensive analyses of the molecular profiling of tumors and matching with clinical phenotypes in the context of existing knowledge described in biomedical literature, registries, and knowledge...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Jan 1, 2024
We introduce an innovative automated system for the search and assessment of genetic variant evidence, meticulously aligned with ACMG guidelines. Leveraging the synergistic power of artificial intelligence (AI), elastic search, and an extensive knowl...
Advances in experimental medicine and biology
Jan 1, 2024
The integration of machine learning (ML) and radiomics is emerging as a pivotal advancement in glioma research, offering novel insights into the diagnosis, prognosis, and treatment of these complex tumors. Radiomics involves the extraction of a multi...
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