AIMC Topic: Precision Medicine

Clear Filters Showing 111 to 120 of 1233 articles

Current AI technologies in cancer diagnostics and treatment.

Molecular cancer
Cancer continues to be a significant international health issue, which demands the invention of new methods for early detection, precise diagnoses, and personalized treatments. Artificial intelligence (AI) has rapidly become a groundbreaking componen...

From Molecular Precision to Clinical Practice: A Comprehensive Review of Bispecific and Trispecific Antibodies in Hematologic Malignancies.

International journal of molecular sciences
Multispecific antibodies have redefined the immunotherapeutic landscape in hematologic malignancies. Bispecific antibodies (BsAbs), which redirect cytotoxic T cells toward malignant targets via dual antigen engagement, are now established components ...

Personalized medication recommendations for Parkinson's disease patients using gated recurrent units and SHAP interpretability.

Scientific reports
Managing Parkinson's disease (PD) through medication can be challenging due to varying symptoms and disease duration. This study aims to demonstrate the potential of sequence-by-sequence algorithms in recommending personalized medication combinations...

Physical and mental health management for the older adult using XGBoost algorithm supported by new media technology: developing personalized health intervention plans using healthcare data from the CLHLS database.

Frontiers in public health
INTRODUCTION: With the increasing aging population, there is a growing need for precise and intelligent health management solutions tailored to older adult individuals. This study proposes a comprehensive digital health management platform that integ...

PRP: pathogenic risk prediction for rare nonsynonymous single nucleotide variants.

Human genetics
Reliable prediction of pathogenic variants plays a crucial role in personalized medicine, which aims to provide accurate diagnosis and individualized treatment using genomic medicine. This study introduces PRP, a pathogenic risk prediction for rare n...

Radiomics applications in the modern management of esophageal squamous cell carcinoma.

Medical oncology (Northwood, London, England)
Esophageal cancer ranks among the most lethal malignancies globally, with China accounting for more than half of worldwide esophageal squamous cell carcinoma (ESCC) cases. Late-stage diagnosis frequently precludes surgical intervention, contributing ...

China Protocol for early screening, precise diagnosis, and individualized treatment of lung cancer.

Signal transduction and targeted therapy
Early screening, diagnosis, and treatment of lung cancer are pivotal in clinical practice since the tumor stage remains the most dominant factor that affects patient survival. Previous initiatives have tried to develop new tools for decision-making o...

Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in precision medicine.

Frontiers in immunology
BACKGROUND: Breast cancer (BC) remains a leading cause of cancer-related mortality among women worldwide. Natural killer (NK) cells play a crucial role in the innate immune system and exhibit significant anti-tumor activity. However, the role of NK c...

Multiomics in Renal Cell Carcinoma: Current Landscape and Future Directions for Precision Medicine.

Current urology reports
PURPOSE OF REVIEW: Renal cell carcinoma (RCC) is a prevalent and increasingly diagnosed malignancy associated with high mortality and recurrence rates. Traditional diagnostic and therapeutic approaches have limitations due to the disease's molecular ...

The development of predictive biomarkers and immunologic markers for breast cancer: current status and future perspectives.

Brazilian journal of biology = Revista brasleira de biologia
Breast cancer is the leading cause of cancer-related mortality among women worldwide. The development of predictive biomarkers and immunologic markers has revolutionized breast cancer diagnosis and treatment, enabling personalized medicine approaches...