AIMC Topic: Precision Medicine

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Future of biomarker evaluation in the realm of artificial intelligence algorithms: application in improved therapeutic stratification of patients with breast and prostate cancer.

Journal of clinical pathology
Clinical workflows in oncology depend on predictive and prognostic biomarkers. However, the growing number of complex biomarkers contributes to costly and delayed decision-making in routine oncology care and treatment. As cancer is expected to rank a...

Translational precision medicine: an industry perspective.

Journal of translational medicine
In the era of precision medicine, digital technologies and artificial intelligence, drug discovery and development face unprecedented opportunities for product and business model innovation, fundamentally changing the traditional approach of how drug...

Plasma Robot Engineering: The Next Generation of Precision Disease Management.

Annals of biomedical engineering
Robotics, once combined with cold atmospheric plasma, represent key elements of the next generation of personalized medicine and contribute to the effective yet immediate response to pandemics. Plasma robots can serve as CAP delivery vehicle to assis...

Artificial intelligence in early drug discovery enabling precision medicine.

Expert opinion on drug discovery
: Precision medicine is the concept of treating diseases based on environmental factors, lifestyles, and molecular profiles of patients. This approach has been found to increase success rates of clinical trials and accelerate drug approvals. However,...

The case for AI-driven cancer clinical trials - The efficacy arm in silico.

Biochimica et biophysica acta. Reviews on cancer
Pharmaceutical agents in oncology currently have high attrition rates from early to late phase clinical trials. Recent advances in computational methods, notably causal artificial intelligence, and availability of rich clinico-genomic databases have ...

A digital highway for data fluidity and data equity in precision medicine.

Biochimica et biophysica acta. Reviews on cancer
Recent technological advances continue to expand the universe of big data in biomedicine along the four axes of variety, veracity, volume, and velocity, fueling innovations in research and discovery while transforming care delivery. These advances al...

Data-driven approaches to advance research and clinical care for pediatric cancer.

Biochimica et biophysica acta. Reviews on cancer
Pediatric cancer is a rare disease with a distinct etiology and mutational landscape compared with adult cancer. Multi-omics profiling of retrospective and prospective cohorts coupled with innovative computational analysis have been instrumental in u...

Swarm Learning for decentralized and confidential clinical machine learning.

Nature
Fast and reliable detection of patients with severe and heterogeneous illnesses is a major goal of precision medicine. Patients with leukaemia can be identified using machine learning on the basis of their blood transcriptomes. However, there is an i...

A deep learning model for detection and tracking in high-throughput images of organoid.

Computers in biology and medicine
Organoid, an in vitro 3D culture, has extremely high similarity with its source organ or tissue, which creates a model in vitro that simulates the in vivo environment. Organoids have been extensively studied in cell biology, precision medicine, drug ...