BACKGROUND: We have explored the potential prefrontal hemodynamic biomarkers to characterize subjects with Traumatic Brain Injury (TBI) by employing the multivariate machine learning approach and introducing a novel task-related hemodynamic response ...
Cortex; a journal devoted to the study of the nervous system and behavior
Jul 15, 2016
Single neurons in the primate orbitofrontal cortex respond when an expected reward is not obtained, and behaviour must change. The human lateral orbitofrontal cortex is activated when non-reward, or loss occurs. The neuronal computation of this negat...
Neurons in higher cortical areas, such as the prefrontal cortex, are often tuned to a variety of sensory and motor variables, and are therefore said to display mixed selectivity. This complexity of single neuron responses can obscure what information...
One major goal in decision neuroscience is to investigate the neuronal mechanisms being responsible for the computation of product preferences. The aim of the present fMRI study was to investigate whether similar patterns of brain activity, reflectin...
International journal of neural systems
Mar 12, 2015
There is wide consensus that the prefrontal cortex (PFC) is able to exert cognitive control on behavior by biasing processing toward task-relevant information and by modulating response selection. This idea is typically framed in terms of top-down in...
International journal of neural systems
Jan 19, 2015
Auditory hallucinations (AH) are a symptom that is most often associated with schizophrenia, but patients with other neuropsychiatric conditions, and even a small percentage of healthy individuals, may also experience AH. Elucidating the neural mecha...
We have developed a Hierarchical Look-Ahead Trajectory Model (HiLAM) that incorporates the firing pattern of medial entorhinal grid cells in a planning circuit that includes interactions with hippocampus and prefrontal cortex. We show the model's fle...
Repetitive transcranial magnetic stimulation (rTMS) is a potential treatment for schizophrenia (SCZ), yet its efficacy and underlying mechanisms remain uncertain. This study evaluates the impact of rTMS targeting the right orbitofrontal cortex (OFC) ...
Neural networks : the official journal of the International Neural Network Society
Sep 1, 2025
Motor sequence learning relies on the synergistic collaboration of multiple brain regions. However, most existing models for motor sequence learning primarily focus on functional-level analyses of sequence memory mechanisms, providing limited neuroph...
With the advancement of artificial intelligence (AI) speech synthesis technology, its application in personalized voice services and its potential role in emotional comfort have become research focal points. This study aims to explore the impact of A...
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