AIMC Topic: Prefrontal Cortex

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Changes in Functional Connectivity Predict Outcome of Repetitive Transcranial Magnetic Stimulation Treatment of Major Depressive Disorder.

Cerebral cortex (New York, N.Y. : 1991)
Repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD) is associated with changes in brain functional connectivity (FC). These changes may be related to the mechanism of action of rTMS and explain the variabi...

Brain stimulation to left prefrontal cortex modulates attentional orienting to gaze cues.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
In social interactions, we rely on non-verbal cues like gaze direction to understand the behaviour of others. How we react to these cues is determined by the degree to which we believe that they originate from an entity with a mind capable of having ...

Predicting Response to Repetitive Transcranial Magnetic Stimulation in Patients With Schizophrenia Using Structural Magnetic Resonance Imaging: A Multisite Machine Learning Analysis.

Schizophrenia bulletin
BACKGROUND: The variability of responses to plasticity-inducing repetitive transcranial magnetic stimulation (rTMS) challenges its successful application in psychiatric care. No objective means currently exists to individually predict the patients' r...

Computing by Robust Transience: How the Fronto-Parietal Network Performs Sequential, Category-Based Decisions.

Neuron
Decision making involves dynamic interplay between internal judgements and external perception, which has been investigated in delayed match-to-category (DMC) experiments. Our analysis of neural recordings shows that, during DMC tasks, LIP and PFC ne...

Using structural MRI to identify individuals at genetic risk for bipolar disorders: a 2-cohort, machine learning study.

Journal of psychiatry & neuroscience : JPN
BACKGROUND: Brain imaging is of limited diagnostic use in psychiatry owing to clinical heterogeneity and low sensitivity/specificity of between-group neuroimaging differences. Machine learning (ML) may better translate neuroimaging to the level of in...