AIMC Topic: Prognosis

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A CT-based deep learning radiomics nomogram outperforms the existing prognostic models for outcome prediction in clear cell renal cell carcinoma: a multicenter study.

European radiology
OBJECTIVES: To develop and validate a CT-based deep learning radiomics nomogram (DLRN) for outcome prediction in clear cell renal cell carcinoma (ccRCC), and its performance was compared with the Stage, Size, Grade, and Necrosis (SSIGN) score, the Un...

Deep Learning Identifies Intelligible Predictors of Poor Prognosis in Chronic Kidney Disease.

IEEE journal of biomedical and health informatics
Early diagnosis and prediction of chronic kidney disease (CKD) progress within a given duration are critical to ensure personalized treatment, which could improve patients' quality of life and prolong survival time. In this study, we explore the inte...

Multi-institutional Prognostic Modeling in Head and Neck Cancer: Evaluating Impact and Generalizability of Deep Learning and Radiomics.

Cancer research communications
UNLABELLED: Artificial intelligence (AI) and machine learning (ML) are becoming critical in developing and deploying personalized medicine and targeted clinical trials. Recent advances in ML have enabled the integration of wider ranges of data includ...

A deep learning MRI-based signature may provide risk-stratification strategies for nasopharyngeal carcinoma.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
OBJECTIVE: As the prognosis of nasopharyngeal carcinoma (NPC) is influenced by various factors, making it difficult for clinical physicians to predict the outcome, the objective of this study was to develop a deep learning-based signature for risk st...

ProGleason-GAN: Conditional progressive growing GAN for prostatic cancer Gleason grade patch synthesis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Prostate cancer is one of the most common diseases affecting men. The main diagnostic and prognostic reference tool is the Gleason scoring system. An expert pathologist assigns a Gleason grade to a sample of prostate tissue....

Transcriptional intra-tumour heterogeneity predicted by deep learning in routine breast histopathology slides provides independent prognostic information.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Intra-tumour heterogeneity (ITH) causes diagnostic challenges and increases the risk for disease recurrence. Quantification of ITH is challenging and has not been demonstrated in large studies. It has previously been shown that deep learn...

A systematic review on machine learning approaches in the diagnosis and prognosis of rare genetic diseases.

Journal of biomedical informatics
BACKGROUND: The diagnosis of rare genetic diseases is often challenging due to the complexity of the genetic underpinnings of these conditions and the limited availability of diagnostic tools. Machine learning (ML) algorithms have the potential to im...

Prediction of posttraumatic functional recovery in middle-aged and older patients through dynamic ensemble selection modeling.

Frontiers in public health
INTRODUCTION: Age-specific risk factors may delay posttraumatic functional recovery; complex interactions exist between these factors. In this study, we investigated the prediction ability of machine learning models for posttraumatic (6 months) funct...

Advanced age is an independent prognostic factor of disease progression in high-risk prostate cancer: results in 180 patients treated with robot-assisted radical prostatectomy and extended pelvic lymph node dissection in a tertiary referral center.

Aging clinical and experimental research
OBJECTIVES: This study aimed to assess more clinical and pathological factors associated with prostate cancer (PCa) progression in high-risk PCa patients treated primarily with robot-assisted radical prostatectomy (RARP) and extended pelvic lymph nod...

Representation of time-varying and time-invariant EMR data and its application in modeling outcome prediction for heart failure patients.

Journal of biomedical informatics
OBJECTIVE: To represent a patient record with both time-invariant and time-varying features as a single vector using an end-to-end deep learning model, and further to predict the kidney failure (KF) status and mortality of heart failure (HF) patients...