AIMC Topic: Programming Languages

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Identification of Gene Regulatory Networks from Single-Cell Expression Data.

Methods in molecular biology (Clifton, N.J.)
Single-cell RNAseq is an emerging technology that allows the quantification of gene expression in individual cells. In plants, single-cell sequencing technology has been applied to generate root cell expression maps under many experimental conditions...

Machine Learning and Perturbation Theory Machine Learning (PTML) in Medicinal Chemistry, Biotechnology, and Nanotechnology.

Current topics in medicinal chemistry
Recently, different authors have reported Perturbation Theory (PT) methods combined with machine learning (ML) to obtain PTML (PT + ML) models. They have applied PTML models to the study of different biological systems. Here we present one state-of-a...

medExtractR: A targeted, customizable approach to medication extraction from electronic health records.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: We developed medExtractR, a natural language processing system to extract medication information from clinical notes. Using a targeted approach, medExtractR focuses on individual drugs to facilitate creation of medication-specific research...

Evaluation of the Fast Healthcare Interoperability Resources (FHIR) Standard for Representation of Knowledge Bases Encoded in the Arden Syntax.

Studies in health technology and informatics
CONTEXT: Arden Syntax is a standard that encodes knowledge as Medical Logic Modules (MLMs) but lacks a standard query data model and terminology.

How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications.

Briefings in bioinformatics
We present a rationale for expanding the presence of the Lisp family of programming languages in bioinformatics and computational biology research. Put simply, Lisp-family languages enable programmers to more quickly write programs that run faster th...

Light-Weighted Automatic Import of Standardized Ontologies into the Content Management System Drupal.

Studies in health technology and informatics
The amount of ontologies, which are utilizable for widespread domains, is growing steadily. BioPortal alone, embraces over 500 published ontologies with nearly 8 million classes. In contrast, the vast informative content of these ontologies is only d...