AIMC Topic: Prospective Studies

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Maternal and umbilical cord plasma purine concentrations after oral carbohydrate loading prior to elective Cesarean delivery under spinal anesthesia: a randomized controlled trial.

BMC pregnancy and childbirth May 10, 2025
OBJECTIVE: To evaluate the effect of preoperative intake of oral carbohydrates versus standard preoperative fasting prior to elective cesarean delivery on plasma purine levels (hypoxanthine, xanthine, and uric acid) and beta-hydroxybutyrate (β-HB) in...
Uric Acid Anesthesia, Spinal Cesarean Section Fetal Blood Adult Humans Purines Preoperative Care Fasting Prospective Studies 3-Hydroxybutyric Acid Diet, Carbohydrate Loading Pregnancy Hypoxanthine Elective Surgical Procedures Female Xanthine
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Improving lower-extremity artery depiction and diagnostic confidence using dual-energy technique and popliteal artery monitoring in dual-low dose CT angiography.

Scientific reports May 9, 2025
To assess the utility of dual-energy CT scanning (DECTs) with popliteal artery (PA) monitoring in dual low-dose (radiation and contrast) lower-extremity CT angiography (LE-CTA). 135 patients undergoing LE-CTA were prospectively included and divided i...
Popliteal Artery Lower Extremity Peripheral Arterial Disease Radiation Dosage Signal-To-Noise Ratio Computed Tomography Angiography Adult Male Humans Middle Aged Prospective Studies Contrast Media Female Aged Aged, 80 and over
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A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection.

Scientific reports May 8, 2025
This study aimed to demonstrate whether plasma galectin-3 could predict the development of postoperative delirium (POD) in patients with acute aortic dissection (AAD). Prospective, observational study. Cardiac surgery intensive care unit. Consecutive...
Aged Male Middle Aged Blood Proteins Humans Postoperative Complications Prospective Studies Galectin 3 ROC Curve Biomarkers Delirium Female Aortic Dissection Risk Factors Galectins
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Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.

Scientific reports May 8, 2025
Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surgical procedures, as these symptoms greatly impact their postoperative experience. Among female patients undergoing laparoscopic surgery, the incidence...
Humans Prospective Studies Female Aged Young Adult Adult Middle Aged Adolescent Double-Blind Method Promethazine Laparoscopy Metoclopramide Postoperative Nausea and Vomiting Antiemetics Gynecologic Surgical Procedures
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Physiological comparison of noninvasive ventilation and high-flow nasal oxygen on inspiratory efforts and tidal volumes after extubation: a randomized crossover trial.

Critical care (London, England) May 8, 2025
BACKGROUND: Extubation failure leading to reintubation is associated with high mortality. In patients at high-risk of extubation failure, clinical practice guidelines recommend prophylactic non-invasive ventilation (NIV) over high-flow nasal oxygen (...
Aged Aged, 80 and over Male Tidal Volume Cross-Over Studies Airway Extubation Oxygen Inhalation Therapy Noninvasive Ventilation Humans Ventilator Weaning Prospective Studies Female
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Interpretable machine learning model for predicting post-hepatectomy liver failure in hepatocellular carcinoma.

Scientific reports May 3, 2025
Post-hepatectomy liver failure (PHLF) is a severe complication following liver surgery. We aimed to develop a novel, interpretable machine learning (ML) model to predict PHLF. We enrolled 312 hepatocellular carcinoma (HCC) patients who underwent hepa...
ROC Curve Liver Neoplasms Carcinoma, Hepatocellular Hepatectomy Liver Failure Adult Male Middle Aged Postoperative Complications Humans Machine Learning Algorithms Prospective Studies Female Aged
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Utilizing explainable machine learning for progression-free survival prediction in high-grade serous ovarian cancer: insights from a prospective cohort study.

International journal of surgery (London, England) May 1, 2025
BACKGROUND: High-grade serous ovarian cancer (HGSOC) remains one of the most challenging gynecological malignancies, with over 70% of ovarian cancer patients ultimately experiencing disease progression. The current prognostic tools for progression-fr...
Neoplasm Grading Progression-Free Survival Cystadenocarcinoma, Serous Humans Female Aged Machine Learning Adult Prospective Studies Middle Aged Prognosis Ovarian Neoplasms
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Detection of Pulmonary Nodules on Ultra-low Dose Chest Computed Tomography With Deep-learning Image Reconstruction Algorithm.

Journal of thoracic imaging May 1, 2025
PURPOSE: To evaluate the accuracy of ultra-low dose (ULD) chest computed tomography (CT), with a radiation exposure equivalent to a 2-view chest x-ray, for pulmonary nodule detection using deep learning image reconstruction (DLIR).
Aged Aged, 80 and over Adult Sensitivity and Specificity Cross-Sectional Studies Humans Algorithms Prospective Studies Tomography, X-Ray Computed Female Radiography, Thoracic Lung Neoplasms Multiple Pulmonary Nodules Solitary Pulmonary Nodule Radiographic Image Interpretation, Computer-Assisted Radiation Dosage Male Middle Aged Lung Deep Learning
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Using Machine Learning to Predict Cognitive Decline in Older Adults From the Chinese Longitudinal Healthy Longevity Survey: Model Development and Validation Study.

JMIR aging Apr 30, 2025
BACKGROUND: Cognitive impairment, indicative of Alzheimer disease and other forms of dementia, significantly deteriorates the quality of life of older adult populations and imposes considerable burdens on families and health care systems worldwide. T...
Longitudinal Studies East Asian People Longevity Aged Humans Aged, 80 and over Machine Learning Male Prospective Studies China Biomarkers Cognitive Dysfunction Female
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Clinical Validation of a Noninvasive Multi-Omics Method for Multicancer Early Detection in Retrospective and Prospective Cohorts.

The Journal of molecular diagnostics : JMD Apr 29, 2025
Recent studies highlight the promise of blood-based multicancer early detection (MCED) tests for identifying asymptomatic patients with cancer. However, most focus on a single cancer hallmark, thus limiting effectiveness because of cancer's heterogen...
Algorithms Prospective Studies Retrospective Studies Female Aged Adult Humans Neoplasms Sensitivity and Specificity Genomics Biomarkers, Tumor Multiomics Male Early Detection of Cancer Middle Aged Whole Genome Sequencing
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