International journal of radiation oncology, biology, physics
Mar 16, 2019
PURPOSE: Recent advances in deep neural networks (DNNs) have unlocked opportunities for their application for automatic image segmentation. We have evaluated a DNN-based algorithm for automatic segmentation of the prostate gland on a large cohort of ...
Computer methods and programs in biomedicine
Mar 14, 2019
BACKGROUND AND OBJECTIVE: Segmenting different tissue components in histopathological images is of great importance for analyzing tissues and tumor environments. In recent years, an encoder-decoder family of convolutional neural networks has increasi...
IMPORTANCE: Proper evaluation of the performance of artificial intelligence techniques in the analysis of digitized medical images is paramount for the adoption of such techniques by the medical community and regulatory agencies.
Multi-parametric MRI (mp-MRI) is considered the best non-invasive imaging modality for diagnosing prostate cancer (PCa). However, mp-MRI for PCa diagnosis is currently limited by the qualitative or semi-quantitative interpretation criteria, leading t...
PURPOSE: Reliable automated segmentation of the prostate is indispensable for image-guided prostate interventions. However, the segmentation task is challenging due to inhomogeneous intensity distributions, variation in prostate anatomy, among other ...
Weakly-supervised learning based on, e.g., partially labelled images or image-tags, is currently attracting significant attention in CNN segmentation as it can mitigate the need for full and laborious pixel/voxel annotations. Enforcing high-order (gl...
PURPOSE: To develop and evaluate a sliding-window convolutional neural network (CNN) for radioactive seed identification in MRI of the prostate after permanent implant brachytherapy.
RATIONALE AND OBJECTIVES: Extraprostatic extension of disease (EPE) has a major role in risk stratification of prostate cancer patients. Currently, pretreatment local staging is performed with MRI, while the gold standard is represented by histopatho...
Computer methods and programs in biomedicine
Dec 29, 2018
BACKGROUND AND OBJECTIVE: Prostate segmentation on Magnetic Resonance (MR) imaging is problematic because disease changes the shape and boundaries of the gland and it can be difficult to separate the prostate from surrounding tissues. We propose an a...
International journal of computer assisted radiology and surgery
Oct 31, 2018
PURPOSE: The fusion of transrectal ultrasound (TRUS) and magnetic resonance (MR) images for guiding targeted prostate biopsy has significantly improved the biopsy yield of aggressive cancers. A key component of MR-TRUS fusion is image registration. H...
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