AIMC Topic: Prostatic Neoplasms

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Incorporating indirect MRI information in a CT-based deep learning model for prostate auto-segmentation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Computed tomography (CT) imaging poses challenges for delineation of soft tissue structures for prostate cancer external beam radiotherapy. Guidelines require the input of magnetic resonance imaging (MRI) information. We devel...

TRUSWorthy: toward clinically applicable deep learning for confident detection of prostate cancer in micro-ultrasound.

International journal of computer assisted radiology and surgery
PURPOSE: While deep learning methods have shown great promise in improving the effectiveness of prostate cancer (PCa) diagnosis by detecting suspicious lesions from trans-rectal ultrasound (TRUS), they must overcome multiple simultaneous challenges. ...

Prediction of adverse pathology in prostate cancer using a multimodal deep learning approach based on [F]PSMA-1007 PET/CT and multiparametric MRI.

European journal of nuclear medicine and molecular imaging
PURPOSE: Accurate prediction of adverse pathology (AP) in prostate cancer (PCa) patients is crucial for formulating effective treatment strategies. This study aims to develop and evaluate a multimodal deep learning model based on [F]PSMA-1007 PET/CT ...

Multi-task learning for automated contouring and dose prediction in radiotherapy.

Physics in medicine and biology
. Deep learning (DL)-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment pl...

Redefining prostate cancer care: innovations and future directions in active surveillance.

Current opinion in urology
PURPOSE OF REVIEW: This review provides a critical analysis of recent advancements in active surveillance (AS), emphasizing updates from major international guidelines and their implications for clinical practice.

Machine learning-based identification of co-expressed genes in prostate cancer and CRPC and construction of prognostic models.

Scientific reports
The objective of this study was to employ machine learning to identify shared differentially expressed genes (DEGs) in prostate cancer (PCa) initiation and castration resistance, aiming to establish a robust prognostic model and enhance understanding...

Z-SSMNet: Zonal-aware Self-supervised Mesh Network for prostate cancer detection and diagnosis with Bi-parametric MRI.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Bi-parametric magnetic resonance imaging (bpMRI) has become a pivotal modality in the detection and diagnosis of clinically significant prostate cancer (csPCa). Developing AI-based systems to identify csPCa using bpMRI can transform prostate cancer (...

Predicting cancer survival at different stages: Insights from fair and explainable machine learning approaches.

International journal of medical informatics
OBJECTIVES: While prior machine learning (ML) models for cancer survivability prediction often treated all cancer stages uniformly, cancer survivability prediction should involve understanding how different stages impact the outcomes. Additionally, t...

Progression-Free Survival Prediction Performance of ChatGPT: Analysis With Real Life Data in Early and Locally Advanced Prostate Cancer.

The Prostate
OBJECTIVE: To evaluate the progression-free survival (PFS) time in patients with early-stage and locally advanced prostate cancer and to compare the estimates provided by ChatGPT with actual survival data.

A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherapy: the ASTuTE protocol.

BMC cancer
BACKGROUND: Androgen deprivation therapy (ADT) improves outcomes in men undergoing definitive radiotherapy for prostate cancer but carries significant toxicities. Clinical parameters alone are insufficient to accurately identify patients who will der...