PURPOSE: The delivery of precision medicine is a primary objective for both clinical and translational investigators. Patients with newly diagnosed prostate cancer (PCa) face the challenge of deciding among multiple initial treatment modalities. The ...
BACKGROUND: An increasing volume of prostate biopsies and a worldwide shortage of urological pathologists puts a strain on pathology departments. Additionally, the high intra-observer and inter-observer variability in grading can result in overtreatm...
BACKGROUND: The Gleason score is the strongest correlating predictor of recurrence for prostate cancer, but has substantial inter-observer variability, limiting its usefulness for individual patients. Specialised urological pathologists have greater ...
Computer methods and programs in biomedicine
Jan 7, 2020
Prostate cancer represents today the most typical example of a pathology whose diagnosis requires multiparametric imaging, a strategy where multiple imaging techniques are combined to reach an acceptable diagnostic performance. However, the reviewing...
PURPOSE: Prostate cancer (PCa) is a major health concern in aging males, and proper management of the disease depends on accurately interpreting pathology specimens. However, reading prostatectomy histopathology slides, which is basically for staging...
PURPOSE: We propose a novel domain-specific loss, which is a differentiable loss function based on the dose-volume histogram (DVH), and combine it with an adversarial loss for the training of deep neural networks. In this study, we trained a neural n...
International journal of computer assisted radiology and surgery
Dec 21, 2019
PURPOSE: In the case of multispecimen study to locate cancer regions, such as in thyroidectomy and prostatectomy, a significant labor-intensive processing is required at a high cost. Pathology diagnosis is usually done by a pathologist observing tiss...
Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has been intens...
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