AIMC Topic: Radiation Dosage

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A deep learning approach to radiation dose estimation.

Physics in medicine and biology
Currently methods for predicting absorbed dose after administering a radiopharmaceutical are rather crude in daily clinical practice. Most importantly, individual tissue density distributions as well as local variations of the concentration of the ra...

Image Quality and Lesion Detection on Deep Learning Reconstruction and Iterative Reconstruction of Submillisievert Chest and Abdominal CT.

AJR. American journal of roentgenology
The objective of this study was to compare image quality and clinically significant lesion detection on deep learning reconstruction (DLR) and iterative reconstruction (IR) images of submillisievert chest and abdominopelvic CT. Our prospective mult...

Projection Space Implementation of Deep Learning-Guided Low-Dose Brain PET Imaging Improves Performance over Implementation in Image Space.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Our purpose was to assess the performance of full-dose (FD) PET image synthesis in both image and sinogram space from low-dose (LD) PET images and sinograms without sacrificing diagnostic quality using deep learning techniques. Clinical brain PET/CT...

Improving Low-contrast Detectability and Noise Texture Pattern for Computed Tomography Using Iterative Reconstruction Accelerated with Machine Learning Method: A Phantom Study.

Academic radiology
RATIONALE AND OBJECTIVES: To evaluate the performance of iterative reconstruction (IR) and filtered back projection (FBP) images in terms of low-contrast detectability at different radiation doses, IR levels, and slice thickness using the mathematica...

Incorporating human and learned domain knowledge into training deep neural networks: A differentiable dose-volume histogram and adversarial inspired framework for generating Pareto optimal dose distributions in radiation therapy.

Medical physics
PURPOSE: We propose a novel domain-specific loss, which is a differentiable loss function based on the dose-volume histogram (DVH), and combine it with an adversarial loss for the training of deep neural networks. In this study, we trained a neural n...

Cardiac substructure segmentation with deep learning for improved cardiac sparing.

Medical physics
PURPOSE: Radiation dose to cardiac substructures is related to radiation-induced heart disease. However, substructures are not considered in radiation therapy planning (RTP) due to poor visualization on CT. Therefore, we developed a novel deep learni...

Synthesizing images from multiple kernels using a deep convolutional neural network.

Medical physics
PURPOSE: Filtering measured projections with a particular convolutional kernel is an essential step in analytic reconstruction of computed tomography (CT) images. A tradeoff between noise and spatial resolution exists for different choices of reconst...

Twin Robotic X-Ray System for 3D Cone-Beam CT of the Wrist: An Evaluation of Image Quality and Radiation Dose.

AJR. American journal of roentgenology
The purpose of this study was to assess image quality and radiation dose of a novel twin robotic x-ray system's 3D cone-beam CT (CBCT) function for the depiction of cadaveric wrists. Sixteen cadaveric wrists were scanned using dedicated low-dose an...