AIMC Topic: Radiotherapy Dosage

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Multi-institutional Knowledge-Based (KB) plan prediction benchmark models for whole breast irradiation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To train and validate KB prediction models by merging a large multi-institutional cohort of whole breast irradiation (WBI) plans using tangential fields.

Clinical Application of Deep Learning-Assisted Needles Reconstruction in Prostate Ultrasound Brachytherapy.

International journal of radiation oncology, biology, physics
PURPOSE: High dose rate (HDR) prostate brachytherapy (BT) procedure requires image-guided needle insertion. Given that general anesthesia is often employed during the procedure, minimizing overall planning time is crucial. In this study, we explore t...

A qualitative, quantitative and dosimetric evaluation of a machine learning-based automatic segmentation method in treatment planning for gastric cancer.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To investigate the performance of a machine learning-based segmentation method for treatment planning of gastric cancer.

Feasibility of reconstructingpatient 3D dose distributions from 2D EPID image data using convolutional neural networks.

Physics in medicine and biology
. The primary purpose of this work is to demonstrate the feasibility of a deep convolutional neural network (dCNN) based algorithm that uses two-dimensional (2D) electronic portal imaging device (EPID) images and CT images as input to reconstruct 3D ...

A unified deep-learning framework for enhanced patient-specific quality assurance of intensity-modulated radiation therapy plans.

Medical physics
BACKGROUND: Modern radiation therapy techniques, such as intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT), use complex fluence modulation strategies to achieve optimal patient dose distribution. Ensuring their ...

Automated treatment planning with deep reinforcement learning for head-and-neck (HN) cancer intensity modulated radiation therapy (IMRT).

Physics in medicine and biology
To develop a deep reinforcement learning (DRL) agent to self-interact with the treatment planning system to automatically generate intensity modulated radiation therapy (IMRT) treatment plans for head-and-neck (HN) cancer with consistent organ-at-ris...

Machine learning based radiomics model to predict radiotherapy induced cardiotoxicity in breast cancer.

Journal of applied clinical medical physics
PURPOSE: Cardiotoxicity is one of the major concerns in breast cancer treatment, significantly affecting patient outcomes. To improve the likelihood of favorable outcomes for breast cancer survivors, it is essential to carefully balance the potential...

Can knowledge-based planning models validated on ethnically diverse patients lead to global standardisation of external beam radiation therapy for locally advanced cervix cancer?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Knowledge-based planning (KBP) can consistently and efficiently create high-quality Volumetric Arc Therapy (VMAT) plans for cervix cancer. This study describes the cross-validation of two KBP models on geographically distinct ...

Validating knowledge-based volumetric modulated arc therapy plans with a multi-institution model (broad model) using a complete open-loop dataset for prostate cancer.

Physical and engineering sciences in medicine
This study examined the characteristics of the broad model (KBP) through a complete open-loop evaluation of volumetric modulated arc therapy (VMAT) plans for prostate cancer in 30 patients at two institutions. KBP, trained using 561 prostate cancer V...

Towards U-Net-based intraoperative 2D dose prediction in high dose rate prostate brachytherapy.

Brachytherapy
BACKGROUND: Poor needle placement in prostate high-dose-rate brachytherapy (HDR-BT) results in sub-optimal dosimetry and mentally predicting these effects during HDR-BT is difficult, creating a barrier to widespread availability of high-quality prost...