AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Quantitative and automatic plan-of-the-day assessment to facilitate adaptive radiotherapy in cervical cancer.

Physics in medicine and biology
To facilitate implementation of plan-of-the-day (POTD) selection for treating locally advanced cervical cancer (LACC), we developed a POTD assessment tool for CBCT-guided radiotherapy (RT). A female pelvis segmentation model (U-Seg3) is combined with...

Deep learning-based automatic dose optimization for brachytherapy.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
PURPOSE: The purpose of this study is to determine the best dose processing method for deep learning-based dose prediction in brachytherapy (BT), as well as to investigate the feasibility of using the inverse dose optimization algorithm to improve tr...

Explainable one-class feature extraction by adaptive resonance for anomaly detection in quality assurance.

PloS one
In this study, we address the inherent challenges in radiotherapy (RT) plan quality assessment (QA). RT, a prevalent cancer treatment, utilizes high-energy beams to target tumors while sparing adjacent healthy tissues. Typically, an RT plan is refine...

Cone-beam computed tomography-based online adaptive radiotherapy of esophageal cancer in the neoadjuvant setting: Dosimetric analysis, toxicity and treatment response.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Chemoradiotherapy (CRT) followed by surgery is a treatment option for esophageal cancer (EC). However, concerns persist regarding cardiopulmonary toxicity and inconsistent daily target coverage due to anatomical changes. To ad...

Feasibility study of a general model for synthetic CT generation in MRI-guided extracranial radiotherapy.

Biomedical physics & engineering express
This study aims to investigate the feasibility of a single general model to synthesize CT images across body sites, thorax, abdomen, and pelvis, to support treatment planning for MRI-only radiotherapy. A total of 157 patients who received MRI-guided ...

Evaluation of deliverable artificial intelligence-based automated volumetric arc radiation therapy planning for whole pelvic radiation in gynecologic cancer.

Scientific reports
This study aimed to develop a deep learning (DL)-based deliverable whole pelvic volumetric arc radiation therapy (VMAT) for patients with gynecologic cancer using a prototype DL-based automated planning support system, named RatoGuide, to evaluate it...

Contouring in transition: perceptions of AI-based autocontouring by radiation oncologists and medical physicists in German-speaking countries.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
BACKGROUND: Artificial intelligence (AI)-based autocontouring software has the potential to revolutionize radiotherapy planning. In recent years, several AI-based autocontouring solutions with many advantages have emerged; however, their clinical use...

Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments.

Journal of applied clinical medical physics
Prostate Stereotactic Ablative Body Radiotherapy (SABR) is an ultra-hypofractionated treatment where small setup errors can lead to higher doses to organs at risk (OARs). Although bowel and bladder preparation protocols reduce inter-fraction variabil...

Reinforcement learning-driven automated head and neck simultaneous integrated boost (SIB) radiation therapy: flexible treatment planning aligned with clinical preferences.

Physics in medicine and biology
Head-and-neck simultaneous integrated boost (SIB) treatment planning using intensity modulated radiation therapy is particularly challenging due to the proximity to organs-at-risk. Depending on the specific clinical conditions, different parotid-spar...

A machine learning toolkit assisted approach for IMRT fluence map optimization: feasibility and advantages.

Biomedical physics & engineering express
. Traditional machine learning (ML) and deep learning (DL) applications in treatment planning rely on complex model architectures and large, high-quality training datasets. However, they cannot fully replace the conventional optimization process. Thi...