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Dose Fractionation, Radiation

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Application of a machine learning method to whole brain white matter injury after radiotherapy for nasopharyngeal carcinoma.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The purpose/aim of this study was to 1) use magnetic resonance diffusion tensor imaging (DTI), fibre bundle/tract-based spatial statistics (TBSS) and machine learning methods to study changes in the white matter (WM) structure and whole b...

A deep learning framework for automatic detection of arbitrarily shaped fiducial markers in intrafraction fluoroscopic images.

Medical physics
PURPOSE: Real-time image-guided adaptive radiation therapy (IGART) requires accurate marker segmentation to resolve three-dimensional (3D) motion based on two-dimensional (2D) fluoroscopic images. Most common marker segmentation methods require prior...

2D ultrasound imaging based intra-fraction respiratory motion tracking for abdominal radiation therapy using machine learning.

Physics in medicine and biology
We have previously developed a robotic ultrasound imaging system for motion monitoring in abdominal radiation therapy. Owing to the slow speed of ultrasound image processing, our previous system could only track abdominal motions under breath-hold. T...

Fast contour propagation for MR-guided prostate radiotherapy using convolutional neural networks.

Medical physics
PURPOSE: To quickly and automatically propagate organ contours from pretreatment to fraction images in magnetic resonance (MR)-guided prostate external-beam radiotherapy.

Developing knowledge-based planning for gynaecological and rectal cancers: a clinical validation of RapidPlan.

Journal of medical radiation sciences
INTRODUCTION: To create and clinically validate knowledge-based planning (KBP) models for gynaecologic (GYN) and rectal cancer patients. Assessment of ecologic generalisability and predictive validity of conventional planning versus single calculatio...

A Prospective Study of Machine Learning-Assisted Radiation Therapy Planning for Patients Receiving 54 Gy to the Brain.

International journal of radiation oncology, biology, physics
PURPOSE: The capacity for machine learning (ML) to facilitate radiation therapy (RT) planning for primary brain tumors has not been described. We evaluated ML-assisted RT planning with regard to clinical acceptability, dosimetric outcomes, and planni...

A competing risks machine learning study of neutron dose, fractionation, age, and sex effects on mortality in 21,000 mice.

Scientific reports
This study explores the impact of densely-ionizing radiation on non-cancer and cancer diseases, focusing on dose, fractionation, age, and sex effects. Using historical mortality data from approximately 21,000 mice exposed to fission neutrons, we empl...

Personalized deep learning auto-segmentation models for adaptive fractionated magnetic resonance-guided radiation therapy of the abdomen.

Medical physics
BACKGROUND: Manual contour corrections during fractionated magnetic resonance (MR)-guided radiotherapy (MRgRT) are time-consuming. Conventional population models for deep learning auto-segmentation might be suboptimal for MRgRT at MR-Linacs since the...

A deep learning model for inter-fraction head and neck anatomical changes in proton therapy.

Physics in medicine and biology
To assess the performance of a probabilistic deep learning based algorithm for predicting inter-fraction anatomical changes in head and neck patients.A probabilistic daily anatomy model (DAM) for head and neck patients DAM (DAM) is built on the varia...