AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Artificial Intelligence in radiotherapy: state of the art and future directions.

Medical oncology (Northwood, London, England)
Recent advances in computing capability allowed the development of sophisticated predictive models to assess complex relationships within observational data, described as Artificial Intelligence. Medicine is one of the several fields of application a...

Error detection using a convolutional neural network with dose difference maps in patient-specific quality assurance for volumetric modulated arc therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
The aim of this study was to evaluate the use of dose difference maps with a convolutional neural network (CNN) to detect multi-leaf collimator (MLC) positional errors in patient-specific quality assurance for volumetric modulated radiation therapy (...

Deep convolutional neural networks for automated segmentation of brain metastases trained on clinical data.

Radiation oncology (London, England)
INTRODUCTION: Deep learning-based algorithms have demonstrated enormous performance in segmentation of medical images. We collected a dataset of multiparametric MRI and contour data acquired for use in radiosurgery, to evaluate the performance of dee...

4D-CT deformable image registration using multiscale unsupervised deep learning.

Physics in medicine and biology
Deformable image registration (DIR) of 4D-CT images is important in multiple radiation therapy applications including motion tracking of soft tissue or fiducial markers, target definition, image fusion, dose accumulation and treatment response evalua...

Conventional vs machine learning-based treatment planning in prostate brachytherapy: Results of a Phase I randomized controlled trial.

Brachytherapy
PURPOSE: The purpose of this study was to evaluate the noninferiority of Day 30 dosimetry between a machine learning-based treatment planning system for prostate low-dose-rate (LDR) brachytherapy and the conventional, manual planning technique. As a ...

A method of using deep learning to predict three-dimensional dose distributions for intensity-modulated radiotherapy of rectal cancer.

Journal of applied clinical medical physics
PURPOSE: To develop and test a three-dimensional (3D) deep learning model for predicting 3D voxel-wise dose distributions for intensity-modulated radiotherapy (IMRT).

DeepDose: Towards a fast dose calculation engine for radiation therapy using deep learning.

Physics in medicine and biology
We present DeepDose, a deep learning framework for fast dose calculations in radiation therapy. Given a patient anatomy and linear-accelerator IMRT multi-leaf-collimator shape or segment, a novel set of physics-based inputs is calculated that encode ...

A convolution neural network for higher resolution dose prediction in prostate volumetric modulated arc therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: This study aims to investigate the feasibility of using convolutional neural networks to predict an accurate and high resolution dose distribution from an approximated and low resolution input dose.

The importance of evaluating the complete automated knowledge-based planning pipeline.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
We determine how prediction methods combine with optimization methods in two-stage knowledge-based planning (KBP) pipelines to produce radiation therapy treatment plans. We trained two dose prediction methods, a generative adversarial network (GAN) a...

A Deep Learning-based correction to EPID dosimetry for attenuation and scatter in the Unity MR-Linac system.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: EPID dosimetry in the Unity MR-Linac system allows for reconstruction of absolute dose distributions within the patient geometry. Dose reconstruction is accurate for the parts of the beam arriving at the EPID through the MRI central unattenu...