p53 immunohistochemistry (IHC) is widely used as a rapid surrogate for detecting mutations, with mutations being a key biomarker for poor outcomes in lymphomas. We developed two algorithms using digital quantification tools to assess p53 expression...
The objective of this study was to compare twenty-six polysomnography (PSG) parameters between the groups utilizing automatic scoring (AS) software and manual scoring (MS) technique. Two MS groups, each comprising technicians with sleep-scoring exper...
Collecting phenotypic data from many individuals is critical to answering fundamental biological questions, particularly in genetics. Yet, whole organismal phenotypic data are still often collected manually; limiting the scale of data generation, pre...
International journal of medical informatics
Oct 1, 2025
This critical review explores two interrelated trends: the rapid increase in studies on machine learning (ML) applications within health informatics and the growing concerns about the reproducibility of these applications across different healthcare ...
IEEE transactions on bio-medical engineering
Oct 1, 2025
Sleep spindles, which are key biomarkers of non-rapid eye movement stage 2 sleep, play a crucial role in predicting outcomes for patients with acute disorders of consciousness (ADOC). However, several critical challenges remain in spindle detection: ...
Dental traumatology : official publication of International Association for Dental Traumatology
Oct 1, 2025
BACKGROUND/AIM: Artificial intelligence (AI) chatbots, also known as large language models (LLMs), have become increasingly common educational tools in healthcare. Although the use of LLMs for emergency dental trauma is gaining popularity, it is cruc...
The Journal of bone and joint surgery. American volume
Sep 17, 2025
BACKGROUND: Patient-education materials (PEMs) are essential to improve health literacy, engagement, and treatment adherence, yet many exceed the recommended readability levels. Therefore, individuals with limited health literacy are at a disadvantag...
Studies in health technology and informatics
Sep 3, 2025
INTRODUCTION: The quality and reproducibility of research results from biological samples are significantly influenced by the pre-analytical variability resulting from different conditions during sample collection, storage and processing. Although nu...
The journal of applied laboratory medicine
Sep 3, 2025
BACKGROUND: Artificial intelligence (AI) models are increasingly used in academic and clinical settings that require information synthesis and decision-making. This study explores the performance, accuracy, and reproducibility of 3 OpenAI models-GPT-...
BACKGROUND: Skin quality has a significant influence on aesthetic perception, yet its clinical evaluation remains subjective and inconsistent. Traditional assessments, such as visual grading and manual scoring, lack reproducibility and fail to captur...
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