Hypertension is the leading risk factor of cardiovascular disease and has profound effects on both the structure and function of the microvasculature. Abnormalities of the retinal vasculature may reflect the degree of microvascular damage due to hype...
Neural networks : the official journal of the International Neural Network Society
Mar 4, 2020
In the early diagnosis of diabetic retinopathy, the morphological attributes of blood vessels play an essential role to construct a retinal computer-aided diagnosis system. However, due to the challenges including limited densely annotated data, inte...
Translational vision science & technology
Feb 14, 2020
PURPOSE: Retinopathy of prematurity (ROP), a leading cause of childhood blindness, is diagnosed by clinical ophthalmoscopic examinations or reading retinal images. Plus disease, defined as abnormal tortuosity and dilation of the posterior retinal blo...
Computer methods and programs in biomedicine
Jan 16, 2020
BACKGROUND: Diabetic retinopathy (DR) is one of the leading causes of blindness globally. Earlier detection and timely treatment of DR are desirable to reduce the incidence and progression of vision loss. Currently, deep learning (DL) approaches have...
PURPOSE: To validate the efficacy of a fully automatic, deep learning-based segmentation algorithm beyond conventional performance metrics by measuring the primary outcome of a clinical trial for macular telangiectasia type 2 (MacTel2).
Clinical & experimental ophthalmology
Nov 11, 2019
BACKGROUND: To define a new quantitative grading criterion for retinal haemorrhages in term newborns based on the segmentation results of a deep convolutional neural network.
The difficulty of obtaining annotations to build training databases still slows down the adoption of recent deep learning approaches for biomedical image analysis. In this paper, we show that we can train a Deep Net to perform 3D volumetric delineati...
Recent studies have shown that convolutional neural networks (CNNs) can be more accurate, efficient and even deeper on their training if they include direct connections from the layers close to the input to those close to the output in order to trans...
Morphology reconstruction of tree-like structures in volumetric images, such as neurons, retinal blood vessels, and bronchi, is of fundamental interest for biomedical research. 3D branch points play an important role in many reconstruction applicatio...
BACKGROUND: The purpose of this study was to develop an automated diagnosis and quantitative analysis system for plus disease. The system provides a diagnostic decision but also performs quantitative analysis of the typical pathological features of t...
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