AIMC Topic:
ROC Curve

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HPO2Vec+: Leveraging heterogeneous knowledge resources to enrich node embeddings for the Human Phenotype Ontology.

Journal of biomedical informatics
BACKGROUND: In precision medicine, deep phenotyping is defined as the precise and comprehensive analysis of phenotypic abnormalities, aiming to acquire a better understanding of the natural history of a disease and its genotype-phenotype associations...

Trader as a new optimization algorithm predicts drug-target interactions efficiently.

Scientific reports
Several machine learning approaches have been proposed for predicting new benefits of the existing drugs. Although these methods have introduced new usage(s) of some medications, efficient methods can lead to more accurate predictions. To this end, w...

Neural networks versus Logistic regression for 30 days all-cause readmission prediction.

Scientific reports
Heart failure (HF) is one of the leading causes of hospital admissions in the US. Readmission within 30 days after a HF hospitalization is both a recognized indicator for disease progression and a source of considerable financial burden to the health...

MR-based artificial intelligence model to assess response to therapy in locally advanced rectal cancer.

European journal of radiology
PURPOSE: To develop and validate an Artificial Intelligence (AI) model based on texture analysis of high-resolution T2 weighted MR images able 1) to predict pathologic Complete Response (CR) and 2) to identify non-responders (NR) among patients with ...

Deep Learning Preoperatively Predicts Value Metrics for Primary Total Knee Arthroplasty: Development and Validation of an Artificial Neural Network Model.

The Journal of arthroplasty
BACKGROUND: The objective is to develop and validate an artificial neural network (ANN) that learns and predicts length of stay (LOS), inpatient charges, and discharge disposition before primary total knee arthroplasty (TKA). The secondary objective ...

Recognition of early and late stages of bladder cancer using metabolites and machine learning.

Metabolomics : Official journal of the Metabolomic Society
INTRODUCTION: Bladder cancer (BCa) is one of the most common and aggressive cancers. It is the sixth most frequently occurring cancer in men and its rate of occurrence increases with age. The current method of BCa diagnosis includes a cystoscopy and ...

Machine learning techniques for personalized breast cancer risk prediction: comparison with the BCRAT and BOADICEA models.

Breast cancer research : BCR
BACKGROUND: Comprehensive breast cancer risk prediction models enable identifying and targeting women at high-risk, while reducing interventions in those at low-risk. Breast cancer risk prediction models used in clinical practice have low discriminat...

MetaNN: accurate classification of host phenotypes from metagenomic data using neural networks.

BMC bioinformatics
BACKGROUND: Microbiome profiles in the human body and environment niches have become publicly available due to recent advances in high-throughput sequencing technologies. Indeed, recent studies have already identified different microbiome profiles in...

Classification of benign and malignant lung nodules from CT images based on hybrid features.

Physics in medicine and biology
The classification of benign and malignant lung nodules has great significance for the early detection of lung cancer, since early diagnosis of nodules can greatly increase patient survival. In this paper, we propose a novel classification method for...

Improved Classification of Blood-Brain-Barrier Drugs Using Deep Learning.

Scientific reports
Blood-Brain-Barrier (BBB) is a strict permeability barrier for maintaining the Central Nervous System (CNS) homeostasis. One of the most important conditions to judge a CNS drug is to figure out whether it has BBB permeability or not. In the past 20 ...