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Effective DNA binding protein prediction by using key features via Chou's general PseAAC.

Journal of theoretical biology
DNA-binding proteins (DBPs) are responsible for several cellular functions, starting from our immunity system to the transport of oxygen. In the recent studies, scientists have used supervised machine learning based methods that use information from ...

Deep Learning to Distinguish Recalled but Benign Mammography Images in Breast Cancer Screening.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: False positives in digital mammography screening lead to high recall rates, resulting in unnecessary medical procedures to patients and health care costs. This study aimed to investigate the revolutionary deep learning methods to distinguish...

Development and validation of a deep-learning algorithm for the detection of polyps during colonoscopy.

Nature biomedical engineering
The detection and removal of precancerous polyps via colonoscopy is the gold standard for the prevention of colon cancer. However, the detection rate of adenomatous polyps can vary significantly among endoscopists. Here, we show that a machine-learni...

Explainable machine-learning predictions for the prevention of hypoxaemia during surgery.

Nature biomedical engineering
Although anaesthesiologists strive to avoid hypoxemia during surgery, reliably predicting future intraoperative hypoxemia is not currently possible. Here, we report the development and testing of a machine-learning-based system that, in real time dur...

Accuracy of an artificial neural network for detecting a regional abnormality in myocardial perfusion SPECT.

Annals of nuclear medicine
OBJECTIVES: The patient-based diagnosis with an artificial neural network (ANN) has shown potential utility for the detection of coronary artery disease; however, the region-based accuracy of the detected regions has not been fully evaluated. The aim...

Comparison of 2 Natural Language Processing Methods for Identification of Bleeding Among Critically Ill Patients.

JAMA network open
IMPORTANCE: To improve patient safety, health care systems need reliable methods to detect adverse events in large patient populations. Events are often described in clinical notes, rather than structured data, which make them difficult to identify o...

Towards a modular decision support system for radiomics: A case study on rectal cancer.

Artificial intelligence in medicine
Following the personalized medicine paradigm, there is a growing interest in medical agents capable of predicting the effect of therapies on patients, by exploiting the amount of data that is now available for each patient. In disciplines like oncolo...

Detecting drug-resistant tuberculosis in chest radiographs.

International journal of computer assisted radiology and surgery
PURPOSE: Tuberculosis is a major global health threat claiming millions of lives each year. While the total number of tuberculosis cases has been decreasing over the last years, the rise of drug-resistant tuberculosis has reduced the chance of contro...