We reveal how implementing the homogeneous, multi-scale mapping frameworks observed in the mammalian brain's mapping systems radically improves the performance of a range of current robotic localization techniques. Roboticists have developed a range ...
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
32711402
To study brain function, preclinical research heavily relies on animal monitoring and the subsequent analyses of behavior. Commercial platforms have enabled semi high-throughput behavioral analyses by automating animal tracking, yet they poorly recog...
Journal of bioinformatics and computational biology
33125294
Accurately identifying organisms based on their partially available genetic material is an important task to explore the phylogenetic diversity in an environment. Specific fragments in the DNA sequence of a living organism have been defined as DNA ba...
Analysis of rodents' behavior/activity is of fundamental importance in many research fields. However, many behavioral experiments still rely on manual scoring, with obvious problems in reproducibility. Despite important advances in video-analysis sys...
Quantification of retinal atrophy, caused by therapeutics and/or light, by manual measurement of retinal layers is labor intensive and time-consuming. In this study, we explored the role of deep learning (DL) in automating the assessment of retinal a...
Rodent progressive cardiomyopathy (PCM) encompasses a constellation of microscopic findings commonly seen as a spontaneous background change in rat and mouse hearts. Primary histologic features of PCM include varying degrees of cardiomyocyte degenera...
International journal of molecular sciences
34070932
The neuronal networks that generate locomotion are well understood in swimming animals such as the lamprey, zebrafish and tadpole. The networks controlling locomotion in tetrapods remain, however, still enigmatic with an intricate motor pattern requi...
The approach undertaken to deliver a Good Laboratory Practice (GLP) validation of whole slide images (WSIs) and the associated workflow for the digital primary evaluation and peer review of a GLP-compliant rodent inhalation toxicity study is describe...