Routine rodent inspection is essential to curbing rat-borne diseases and infrastructure damages within the built environment. Rodents find false ceilings to be a perfect spot to seek shelter and construct their habitats. However, a manual false ceili...
The approach undertaken to deliver a Good Laboratory Practice (GLP) validation of whole slide images (WSIs) and the associated workflow for the digital primary evaluation and peer review of a GLP-compliant rodent inhalation toxicity study is describe...
International journal of molecular sciences
May 30, 2021
The neuronal networks that generate locomotion are well understood in swimming animals such as the lamprey, zebrafish and tadpole. The networks controlling locomotion in tetrapods remain, however, still enigmatic with an intricate motor pattern requi...
Quantification of retinal atrophy, caused by therapeutics and/or light, by manual measurement of retinal layers is labor intensive and time-consuming. In this study, we explored the role of deep learning (DL) in automating the assessment of retinal a...
Rodent progressive cardiomyopathy (PCM) encompasses a constellation of microscopic findings commonly seen as a spontaneous background change in rat and mouse hearts. Primary histologic features of PCM include varying degrees of cardiomyocyte degenera...
Journal of bioinformatics and computational biology
Oct 29, 2020
Accurately identifying organisms based on their partially available genetic material is an important task to explore the phylogenetic diversity in an environment. Specific fragments in the DNA sequence of a living organism have been defined as DNA ba...
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Jul 25, 2020
To study brain function, preclinical research heavily relies on animal monitoring and the subsequent analyses of behavior. Commercial platforms have enabled semi high-throughput behavioral analyses by automating animal tracking, yet they poorly recog...
We reveal how implementing the homogeneous, multi-scale mapping frameworks observed in the mammalian brain's mapping systems radically improves the performance of a range of current robotic localization techniques. Roboticists have developed a range ...
Automated observation and analysis of rodent behavior is important to facilitate research progress in neuroscience and pharmacology. Available automated systems lack adaptivity and can benefit from advances in AI. In this work we compare a state-of-t...
The cellular and synaptic architecture of the rodent hippocampus has been described in thousands of peer-reviewed publications. However, no human- or machine-readable public catalog of synaptic electrophysiology data exists for this or any other neur...
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