AIMC Topic: Rodentia

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AI Enabled IoRT Framework for Rodent Activity Monitoring in a False Ceiling Environment.

Sensors (Basel, Switzerland)
Routine rodent inspection is essential to curbing rat-borne diseases and infrastructure damages within the built environment. Rodents find false ceilings to be a perfect spot to seek shelter and construct their habitats. However, a manual false ceili...

Utilizing Whole Slide Images for the Primary Evaluation and Peer Review of a GLP-Compliant Rodent Toxicology Study.

Toxicologic pathology
The approach undertaken to deliver a Good Laboratory Practice (GLP) validation of whole slide images (WSIs) and the associated workflow for the digital primary evaluation and peer review of a GLP-compliant rodent inhalation toxicity study is describe...

The CPGs for Limbed Locomotion-Facts and Fiction.

International journal of molecular sciences
The neuronal networks that generate locomotion are well understood in swimming animals such as the lamprey, zebrafish and tadpole. The networks controlling locomotion in tetrapods remain, however, still enigmatic with an intricate motor pattern requi...

Deep Learning in Toxicologic Pathology: A New Approach to Evaluate Rodent Retinal Atrophy.

Toxicologic pathology
Quantification of retinal atrophy, caused by therapeutics and/or light, by manual measurement of retinal layers is labor intensive and time-consuming. In this study, we explored the role of deep learning (DL) in automating the assessment of retinal a...

Using Artificial Intelligence to Detect, Classify, and Objectively Score Severity of Rodent Cardiomyopathy.

Toxicologic pathology
Rodent progressive cardiomyopathy (PCM) encompasses a constellation of microscopic findings commonly seen as a spontaneous background change in rat and mouse hearts. Primary histologic features of PCM include varying degrees of cardiomyocyte degenera...

Scalable classification of organisms into a taxonomy using hierarchical supervised learners.

Journal of bioinformatics and computational biology
Accurately identifying organisms based on their partially available genetic material is an important task to explore the phylogenetic diversity in an environment. Specific fragments in the DNA sequence of a living organism have been defined as DNA ba...

Deep learning-based behavioral analysis reaches human accuracy and is capable of outperforming commercial solutions.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
To study brain function, preclinical research heavily relies on animal monitoring and the subsequent analyses of behavior. Commercial platforms have enabled semi high-throughput behavioral analyses by automating animal tracking, yet they poorly recog...

Bio-inspired multi-scale fusion.

Biological cybernetics
We reveal how implementing the homogeneous, multi-scale mapping frameworks observed in the mammalian brain's mapping systems radically improves the performance of a range of current robotic localization techniques. Roboticists have developed a range ...

Deep learning improves automated rodent behavior recognition within a specific experimental setup.

Journal of neuroscience methods
Automated observation and analysis of rodent behavior is important to facilitate research progress in neuroscience and pharmacology. Available automated systems lack adaptivity and can benefit from advances in AI. In this work we compare a state-of-t...

A comprehensive knowledge base of synaptic electrophysiology in the rodent hippocampal formation.

Hippocampus
The cellular and synaptic architecture of the rodent hippocampus has been described in thousands of peer-reviewed publications. However, no human- or machine-readable public catalog of synaptic electrophysiology data exists for this or any other neur...