AIMC Topic: Schizophrenia
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Diagnosis of Schizophrenia Based on Deep Learning Using fMRI.
Computational and mathematical methods in medicine
Nov 9, 2021
Schizophrenia is a brain disease that frequently occurs in young people. Early diagnosis and treatment can reduce family burdens and reduce social costs. There is no objective evaluation index for schizophrenia. In order to improve the classification...
Hollow-tree super: A directional and scalable approach for feature importance in boosted tree models.
PloS one
Oct 25, 2021
PURPOSE: Current limitations in methodologies used throughout machine-learning to investigate feature importance in boosted tree modelling prevent the effective scaling to datasets with a large number of features, particularly when one is investigati...
Color painting predicts clinical symptoms in chronic schizophrenia patients via deep learning.
BMC psychiatry
Oct 22, 2021
BACKGROUND: Individuals with psychiatric disorders perceive the world differently. Previous studies indicated impaired color vision and weakened color discrimination ability in psychotic patients. Examining the paintings from psychotic patients can m...
Causal pathways to social and occupational functioning in the first episode of schizophrenia: uncovering unmet treatment needs.
Psychological medicine
Oct 8, 2021
BACKGROUND: We aimed to identify unmet treatment needs for improving social and occupational functioning in early schizophrenia using a data-driven causal discovery analysis.
Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction.
Nature communications
Sep 6, 2021
A promise of genomics in precision medicine is to provide individualized genetic risk predictions. Polygenic risk scores (PRS), computed by aggregating effects from many genomic variants, have been developed as a useful tool in complex disease resear...
Machine learning approach to measurement of criticism: The core dimension of expressed emotion.
Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)
Aug 19, 2021
Expressed emotion (EE), a measure of the family's emotional climate, is a fundamental measure in caregiving research. A core dimension of EE is the level of criticism expressed by the caregiver to the care recipient, with a high level of criticism a ...
Sch-net: a deep learning architecture for automatic detection of schizophrenia.
Biomedical engineering online
Aug 3, 2021
BACKGROUND: Schizophrenia is a chronic and severe mental disease, which largely influences the daily life and work of patients. Clinically, schizophrenia with negative symptoms is usually misdiagnosed. The diagnosis is also dependent on the experienc...
Improving the predictive potential of diffusion MRI in schizophrenia using normative models-Towards subject-level classification.
Human brain mapping
Jul 29, 2021
Diffusion MRI studies consistently report group differences in white matter between individuals diagnosed with schizophrenia and healthy controls. Nevertheless, the abnormalities found at the group-level are often not observed at the individual level...
Analysis of cognitive impairment in schizophrenia based on machine learning: Interaction between psychological stress and immune system.
Neuroscience letters
Jun 24, 2021
The interaction between psychological stress and immune system may be associated with the cognitive impairment of schizophrenia. To employ machine learning algorithms to examine patterns of stress-immune networks with cognitive impairment in chronic ...
Going deep into schizophrenia with artificial intelligence.
Schizophrenia research
Jun 5, 2021
Despite years of research, the mechanisms governing the onset, relapse, symptomatology, and treatment of schizophrenia (SZ) remain elusive. The lack of appropriate analytic tools to deal with the heterogeneity and complexity of SZ may be one of the r...
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