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Schizophrenia

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Identification of Diagnostic Schizophrenia Biomarkers Based on the Assessment of Immune and Systemic Inflammation Parameters Using Machine Learning Modeling.

Sovremennye tekhnologii v meditsine
UNLABELLED: Disorders of systemic immunity and immune processes in the brain have now been shown to play an essential role in the development and progression of schizophrenia. Nevertheless, only a few works were devoted to the study of some immune pa...

On the improvement of schizophrenia detection with optical coherence tomography data using deep neural networks and aggregation functions.

Scientific reports
Schizophrenia is a serious mental disorder with a complex neurobiological background and a well-defined psychopathological picture. Despite many efforts, a definitive disease biomarker has still not been identified. One of the promising candidates fo...

Estimating the Prevalence of Schizophrenia in the General Population of Japan Using an Artificial Neural Network-Based Schizophrenia Classifier: Web-Based Cross-Sectional Survey.

JMIR formative research
BACKGROUND: Estimating the prevalence of schizophrenia in the general population remains a challenge worldwide, as well as in Japan. Few studies have estimated schizophrenia prevalence in the Japanese population and have often relied on reports from ...

Semantic abnormalities in schizophrenia and bipolar disorder: A natural language processing approach.

Science progress
INTRODUCTION: The diagnostic boundaries between schizophrenia and bipolar disorder are controversial due to the ambiguity of psychiatric nosology. From this perspective, it is noteworthy that formal thought disorder has historically been considered p...

A comparative machine learning study of schizophrenia biomarkers derived from functional connectivity.

Scientific reports
Functional connectivity holds promise as a biomarker of schizophrenia. Yet, the high dimensionality of predictive models trained on functional connectomes, combined with small sample sizes in clinical research, increases the risk of overfitting. Rece...

MO-GCN: A multi-omics graph convolutional network for discriminative analysis of schizophrenia.

Brain research bulletin
The methodology of machine learning with multi-omics data has been widely adopted in the discriminative analyses of schizophrenia, but most of these studies ignored the cooperative interactions and topological attributes of multi-omics networks. In t...

Schizophrenia more employable than depression? Language-based artificial intelligence model ratings for employability of psychiatric diagnoses and somatic and healthy controls.

PloS one
Artificial Intelligence (AI) assists recruiting and job searching. Such systems can be biased against certain characteristics. This results in potential misrepresentations and consequent inequalities related to people with mental health disorders. He...

Diagnosis of Schizophrenia and Its Subtypes Using MRI and Machine Learning.

Brain and behavior
PURPOSE: The neurobiological heterogeneity present in schizophrenia remains poorly understood. This likely contributes to the limited success of existing treatments and the observed variability in treatment responses. Our objective was to employ magn...

Predicting antipsychotic responsiveness using a machine learning classifier trained on plasma levels of inflammatory markers in schizophrenia.

Translational psychiatry
We apply machine learning techniques to navigate the multifaceted landscape of schizophrenia. Our method entails the development of predictive models, emphasizing peripheral inflammatory biomarkers, which are classified into treatment response subgro...

Schizophrenia recognition based on three-dimensional adaptive graph convolutional neural network.

Scientific reports
Previous deep learning-based brain network research has made significant progress in understanding the pathophysiology of schizophrenia. However, it ignores the three-dimensional spatial characteristics of EEG signals and cannot dynamically learn the...