AIMC Topic: Sepsis

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Machine learning for predicting mortality in adult critically ill patients with Sepsis: A systematic review.

Journal of critical care
INTRODUCTION: Various Machine Learning (ML) models have been used to predict sepsis-associated mortality. We conducted a systematic review to evaluate the methodologies employed in studies to predict mortality among patients with sepsis.

Machine learning for the prediction of 1-year mortality in patients with sepsis-associated acute kidney injury.

BMC medical informatics and decision making
INTRODUCTION: Sepsis-associated acute kidney injury (SA-AKI) is strongly associated with poor prognosis. We aimed to build a machine learning (ML)-based clinical model to predict 1-year mortality in patients with SA-AKI.

A proof of concept for microcirculation monitoring using machine learning based hyperspectral imaging in critically ill patients: a monocentric observational study.

Critical care (London, England)
BACKGROUND: Impaired microcirculation is a cornerstone of sepsis development and leads to reduced tissue oxygenation, influenced by fluid and catecholamine administration during treatment. Hyperspectral imaging (HSI) is a non-invasive bedside technol...

Development and external validation of machine learning-based models to predict patients with cellulitis developing sepsis during hospitalisation.

BMJ open
OBJECTIVE: Cellulitis is the most common cause of skin-related hospitalisations, and the mortality of patients with sepsis remains high. Some stratification models have been developed, but their performance in external validation has been unsatisfact...

Evaluating Explanations From AI Algorithms for Clinical Decision-Making: A Social Science-Based Approach.

IEEE journal of biomedical and health informatics
Explainable Artificial Intelligence (XAI) techniques generate explanations for predictions from AI models. These explanations can be evaluated for (i) faithfulness to the prediction, i.e., its correctness about the reasons for prediction, and (ii) us...

Integrated multi-omics analysis and machine learning developed diagnostic markers and prognostic model based on Efferocytosis-associated signatures for septic cardiomyopathy.

Clinical immunology (Orlando, Fla.)
Septic cardiomyopathy (SCM) is characterized by an abnormal inflammatory response and increased mortality. The role of efferocytosis in SCM is not well understood. We used integrated multi-omics analysis to explore the clinical and genetic roles of e...

Sepsis mortality prediction with Machine Learning Tecniques.

Medicina intensiva
OBJECTIVE: To develop a sepsis death classification model based on machine learning techniques for patients admitted to the Intensive Care Unit (ICU).

Unraveling the genetic and molecular landscape of sepsis and acute kidney injury: A comprehensive GWAS and machine learning approach.

International immunopharmacology
OBJECTIVES: This study aimed to explore the underlying mechanisms of sepsis and acute kidney injury (AKI), including sepsis-associated AKI (SA-AKI), a frequent complication in critically ill sepsis patients.

Random forest differentiation of Escherichia coli in elderly sepsis using biomarkers and infectious sites.

Scientific reports
This study addresses the challenge of accurately diagnosing sepsis subtypes in elderly patients, particularly distinguishing between Escherichia coli (E. coli) and non-E. coli infections. Utilizing machine learning, we conducted a retrospective analy...

Deciphering Abnormal Platelet Subpopulations in COVID-19, Sepsis and Systemic Lupus Erythematosus through Machine Learning and Single-Cell Transcriptomics.

International journal of molecular sciences
This study focuses on understanding the transcriptional heterogeneity of activated platelets and its impact on diseases such as sepsis, COVID-19, and systemic lupus erythematosus (SLE). Recognizing the limited knowledge in this area, our research aim...