AIMC Topic: Software

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Software technical debt prediction based on complex software networks.

PloS one Jun 9, 2025
Technical debt prediction (TDP) is crucial for the long-term maintainability of software. In the literature, many machine-learning based TDP models have been proposed; they used TD-related metrics as input features for machine-learning classifiers to...
Humans Machine Learning Algorithms Software
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PhenoDP: leveraging deep learning for phenotype-based case reporting, disease ranking, and symptom recommendation.

Genome medicine Jun 6, 2025
BACKGROUND: Current phenotype-based diagnostic tools often struggle with accurate disease prioritization due to incomplete phenotypic data and the complexity of rare disease presentations. Additionally, they lack the ability to generate patient-cente...
Phenotype Humans Deep Learning Software
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A descriptor-free machine learning framework to improve antigen discovery for bacterial pathogens.

PloS one Jun 5, 2025
Identifying protective antigens (PAs), i.e., targets for bacterial vaccines, is challenging as conducting in-vivo tests at the proteome scale is impractical. Reverse Vaccinology (RV) aids in narrowing down the pool of candidates through computational...
Bacterial Vaccines Machine Learning Vaccinology Neural Networks, Computer Bacteria Software Computational Biology Antigens, Bacterial
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Digital removal of dermal denticle layer using geometric AI from 3D CT scans of shark craniofacial structures enhances anatomical precision.

Scientific reports Jun 4, 2025
Craniofacial morphometrics in sharks provide crucial insights into evolutionary history, geographical variation, sexual dimorphism, and developmental patterns. However, the fragile cartilaginous nature of shark craniofacial skeleton poses significant...
Sharks Image Processing, Computer-Assisted Skull Artificial Intelligence Software Algorithms Animals Tomography, X-Ray Computed Male Female Imaging, Three-Dimensional
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Comparative analysis of AI chatbot (ChatGPT-4.0 and Microsoft Copilot) and expert responses to common orthodontic questions: patient and orthodontist evaluations.

BMC oral health Jun 3, 2025
OBJECTIVE: The aim of this study was to evaluate the adequacy of responses provided by experts and artificial intelligence-based chatbots (ChatGPT-4.0 and Microsoft Copilot) to frequently asked orthodontic questions, utilizing scores assigned by pati...
Software Female Male Surveys and Questionnaires Adult Humans Artificial Intelligence Orthodontists Generative Artificial Intelligence Orthodontics Patient Satisfaction
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Application research of artificial intelligence software in the analysis of thyroid nodule ultrasound image characteristics.

PloS one Jun 2, 2025
Thyroid nodule, as a common clinical endocrine disease, has become increasingly prevalent worldwide. Ultrasound, as the premier method of thyroid imaging, plays an important role in accurately diagnosing and managing thyroid nodules. However, there i...
Thyroid Nodule Artificial Intelligence Middle Aged Image Processing, Computer-Assisted Software Ultrasonography Image Interpretation, Computer-Assisted Adult Male Female Humans
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AMPGen: an evolutionary information-reserved and diffusion-driven generative model for de novo design of antimicrobial peptides.

Communications biology May 30, 2025
The rapid advancement of artificial intelligence (AI) has enabled de novo design of functional proteins, circumventing the reliance on natural templates or sequencing databases. However, current protein design models are ineffective in generating pro...
Antimicrobial Peptides Artificial Intelligence Evolution, Molecular Sequence Alignment Anti-Bacterial Agents Software Drug Design
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Requirement Analysis for Data-Driven Electroencephalography Seizure Monitoring Software to Enhance Quality and Decision Making in Digital Care Pathways for Epilepsy: A Feasibility Study from the Perspectives of Health Care Professionals.

JMIR human factors May 30, 2025
BACKGROUND: Abnormal brain activity is the source of epileptic seizures, which can present a variety of symptoms and influence patients' quality of life. Therefore, it is critical to track epileptic seizures, diagnose them, and provide potential ther...
Humans Seizures Software Feasibility Studies Focus Groups Electroencephalography Epilepsy Health Personnel
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PRP: pathogenic risk prediction for rare nonsynonymous single nucleotide variants.

Human genetics May 29, 2025
Reliable prediction of pathogenic variants plays a crucial role in personalized medicine, which aims to provide accurate diagnosis and individualized treatment using genomic medicine. This study introduces PRP, a pathogenic risk prediction for rare n...
Humans Machine Learning Computational Biology Precision Medicine Software Genetic Predisposition to Disease Algorithms Polymorphism, Single Nucleotide
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scE2EGAE: enhancing single-cell RNA-Seq data analysis through an end-to-end cell-graph-learnable graph autoencoder with differentiable edge sampling.

Biology direct May 27, 2025
BACKGROUND: Single-cell RNA sequencing (scRNA-Seq) technology reveals biological processes and molecular-level genomic information among individual cells. Numerous computational methods, including methods based on graph neural networks (GNNs), have b...
Algorithms Single-Cell Analysis RNA-Seq Neural Networks, Computer Software Autoencoder Single-Cell Gene Expression Analysis Sequence Analysis, RNA Humans
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