AIMC Topic: Specimen Handling

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Highly accurate and explainable detection of specimen mix-up using a machine learning model.

Clinical chemistry and laboratory medicine
Background Delta check is widely used for detecting specimen mix-ups. Owing to the inadequate specificity and sparseness of the absolute incidence of mix-ups, the positive predictive value (PPV) of delta check is considerably low as it is labor consu...

Ultra-gentle soft robotic fingers induce minimal transcriptomic response in a fragile marine animal.

Current biology : CB
Tessler et al. demonstrate that a 'soft' robot causes less stress to a jellyfish while handling compared to a traditional 'hard' robot.

Automated sample preparation with SP3 for low-input clinical proteomics.

Molecular systems biology
High-throughput and streamlined workflows are essential in clinical proteomics for standardized processing of samples from a variety of sources, including fresh-frozen tissue, FFPE tissue, or blood. To reach this goal, we have implemented single-pot ...

In Vitro Evaluation of the Fresenius Kabi CATSmart Autotransfusion System.

The journal of extra-corporeal technology
Use of autotransfusion systems to collect, wash, and concentrate shed blood during surgical procedures is a widely used method for reducing postoperative anemia and the need for blood transfusions. The aim of this study was to evaluate the CATSmart C...

[Feasibility Study for Storage and Re-Utilization of Circulating Tumor Cells (CTCs)].

Rinsho byori. The Japanese journal of clinical pathology
BACKGROUND: In this era of precision medicine, monitoring patients requires not only real time but also longitudinal sequence of samples at various time points. Based on this background, we focused on conditioned circumstances on fixation and storage...

Multiplexed TEM Specimen Preparation and Analysis of Plasmonic Nanoparticles.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
We describe a system for rapidly screening hundreds of nanoparticle samples using transmission electron microscopy (TEM). The system uses a liquid handling robot to place up to 96 individual samples onto a single standard TEM grid at separate locatio...