Pathogenic bacteria pose serious threats to public health and environmental safety. Conventional colony counting, a standard method for bacterial detection, is time-consuming and unsuitable for rapid on-site detection. In this work, a flexible ACH/Ag...
Traditional histopathological analysis of cells and tissue relies on morphological features from stained biopsy samples, which fail to leverage the wealth of chemical information about the underlying pathological states. Raman spectroscopy, a form of...
The overused quinolone antibiotics in animal husbandry and clinical medicine pose a growing threat for global health as they enter ecosystem via agricultural discharge and medical wastewater. Consequently, risk assessment for environmental and human ...
Gastric cancer (GC) remains one of the most prevalent and lethal malignancies worldwide, necessitating the development of efficient, non-invasive methods for early detection. In this study, a serum diagnostic approach based on shell-isolated nanopart...
Monitoring dynamic changes in drugs and their metabolites is essential for basic research, preclinical evaluation, and clinical applications. Surface-enhanced Raman spectroscopy (SERS) has shown great promise in therapeutic drug monitoring due to its...
In this paper, an innovative approach is proposed to achieve no-preparation, rapid, and accurate identification of red wine brands by combining Surface-Enhanced Raman Scattering (SERS) spectroscopy with machine learning. SERS detects trace molecular ...
Rapid and label-free evaluation of induced pluripotent stem cell (iPSC) pluripotency is critical for advancing regenerative medicine and clinical applications. Although traditional genomics- and proteomics-based pluripotency assessment methods are re...
The escalating global threat of antimicrobial resistance (AMR) necessitates a paradigm shift towards rapid and scalable diagnostic technologies. Conventional antimicrobial susceptibility testing (AST) methods, while reliable, are hindered by prolonge...
Intraductal carcinoma of the prostate (IDC-P) is a very aggressive histopathological subtype of prostate cancer (PCa) that is strongly associated with poor clinical outcomes but for which no accurate biomarkers exist. Here, we demonstrate a novel app...
Neurofilament light chain (NfL), a cytoskeletal protein released during neuronal injury, is a promising biomarker, with elevated levels consistently associated with disease severity and progression in multiple neurological conditions, including Alzhe...
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