AIMC Topic: Spectrum Analysis, Raman

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Study of interaction in dual-species biofilm of Candida glabrata and Klebsiella pneumoniae co-isolated from peripheral venous catheter using Raman characterization mapping and machine learning algorithms.

Microbial pathogenesis
Polymicrobial biofilm infections, especially associated with medical devices such as peripheral venous catheters, are challenging in clinical settings for treatment and management. In this study, we examined the mixed biofilm formed by Candida glabra...

Unsupervised self-organising map classification of Raman spectra from prostate cell lines uncovers substratified prostate cancer disease states.

Scientific reports
Prostate cancer is a disease which poses an interesting clinical question: Should it be treated? Only a small subset of prostate cancers are aggressive and require removal and treatment to prevent metastatic spread. However, conventional diagnostics ...

Raman spectroscopy integrated with machine learning techniques to improve industrial sorting of Waste Electric and Electronic Equipment (WEEE) plastics.

Journal of environmental management
Current industrial separation and sorting technologies struggle to efficiently identify and classify a large part of Waste of Electric and Electronic Equipment (WEEE) plastics due to their high content of certain additives. In this study, Raman spect...

Radial SERS acquisition on coffee ring for Serum-based breast cancer diagnosis through Multilayer Perceptron.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The coffee-ring effect, involving spontaneous solute separation, has demonstrated promising potential in the context of patient serum analysis. In this study, an approach leveraging the coffee-ring-based analyte redistribution was developed for spect...

Implementation of machine learning tool for continued process verification of process chromatography unit operation.

Journal of chromatography. A
Recent advancements in technology, such as the emergence of artificial intelligence (AI) and machine learning (ML), have facilitated the progression of the biopharmaceutical industry toward the implementation of Industry 4.0. As per the guidelines se...

Identification of Phosphodiesterase type 5 inhibitors (PDE5is) analogues using surface-enhanced Raman scattering and machine learning algorithm.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Phosphodiesterase type 5 inhibitors (PDE5is), primarily used for the treatment of erectile dysfunction, have been severely misused in recent years, posing a threat to public health and safety. This study developed a method that combines Surface-enhan...

Stimulated Raman Histology and Artificial Intelligence Provide Near Real-Time Interpretation of Radical Prostatectomy Surgical Margins.

The Journal of urology
PURPOSE: Balancing surgical margins and functional outcomes is crucial during radical prostatectomy for prostate cancer. Stimulated Raman histology (SRH) is a novel, real-time imaging technique that provides histologic images of fresh, unprocessed, a...

Convolutional neural network-assisted Raman spectroscopy for high-precision diagnosis of glioblastoma.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Glioblastoma multiforme (GBM) is the most lethal intracranial tumor with a median survival of approximately 15 months. Due to its highly invasive properties, it is particularly difficult to accurately identify the tumor margins intraoperatively. The ...

Rapid and high accuracy identification of culture medium by CNN of Raman spectra.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Culture media are widely used for biological research and production. It is essential for the growth of microorganisms, cells, or tissues. It includes complex components like carbohydrates, proteins, vitamins, and minerals. The media's consistency is...

Machine Learning-Assisted "Shrink-Restricted" SERS Strategy for Classification of Environmental Nanoplastic-Induced Cell Death.

Environmental science & technology
The biotoxicity of nanoplastics (NPs), especially from environmental sources, and "NPs carrier effect" are in the early stages of research. This study presents a machine learning-assisted "shrink-restricted" SERS strategy (SRSS) to monitor molecular ...