In recent years, there has been an intense debate about how learning in biological neural networks (BNNs) differs from learning in artificial neural networks. It is often argued that the updating of connections in the brain relies only on local infor...
Mathematical biosciences and engineering : MBE
Aug 14, 2023
Stochastic modeling predicts various outcomes from stochasticity in the data, parameters and dynamical system. Stochastic models are deemed more appropriate than deterministic models accounting in terms of essential and practical information about a ...
Generalization is one of the most important problems in deep learning, where there exist many low-loss solutions due to overparametrization. Previous empirical studies showed a strong correlation between flatness of the loss landscape at a solution a...
Proceedings of the National Academy of Sciences of the United States of America
Oct 26, 2021
In this paper, we introduce the , a nonconvex, yet analytically tractable, optimization program, in a quest to better understand deep neural networks that are trained for a sufficiently long time. As the name suggests, this model is derived by isolat...
Mathematical biosciences and engineering : MBE
Sep 27, 2021
In this paper, a reaction-diffusion vegetation-water system with time-varying delay, impulse and Lévy jump is proposed. The existence and uniqueness of the positive solution are proved. Meanwhile, mainly through the principle of comparison, we obtain...
Many sensory pathways in the brain include sparsely active populations of neurons downstream from the input stimuli. The biological purpose of this expanded structure is unclear, but it may be beneficial due to the increased expressive power of the n...
The problem of distinguishing deterministic chaos from non-chaotic dynamics has been an area of active research in time series analysis. Since noise contamination is unavoidable, it renders deterministic chaotic dynamics corrupted by noise to appear ...
Access to large-scale genomics datasets has increased the utility of hypothesis-free genome-wide analyses. However, gene signals are often insufficiently powered to reach experiment-wide significance, triggering a process of laborious triaging of gen...
We suggest a new method for building data-driven dynamical models from observed multidimensional time series. The method is based on a recurrent neural network with specific structure, which allows for the joint reconstruction of both a low-dimension...
PURPOSE: The prediction of clinical outcomes for patients with cancer is central to precision medicine and the design of clinical trials. We developed and validated machine-learning models for three important clinical end points in patients with adva...