AIMC Topic: tert-Butylhydroperoxide

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Machine learning reveals genes impacting oxidative stress resistance across yeasts.

Nature communications Jul 1, 2025
Reactive oxygen species (ROS) are highly reactive molecules encountered by yeasts during routine metabolism and during interactions with other organisms, including host infection. Here, we characterize the variation in resistance to the ROS-inducing ...
Machine Learning Oxidative Stress Reactive Oxygen Species Fungal Proteins Saccharomyces cerevisiae Gene Expression Regulation, Fungal Genes, Fungal tert-Butylhydroperoxide Oxidoreductases Kluyveromyces Mannosyltransferases
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Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning.

Biochimica et biophysica acta Nov 13, 2014
Understanding the processes of mitochondrial dynamics (fission, fusion, biogenesis, and mitophagy) has been hampered by the lack of automated, deterministic methods to measure mitochondrial morphology from microscopic images. A method to quantify mit...
Artificial Intelligence Phenotype Animals Imaging, Three-Dimensional Mice Cell Line Cell Survival Membrane Potential, Mitochondrial Oxidants Mitochondria Sodium-Potassium-Exchanging ATPase Stress, Physiological Cell Membrane Electron Transport tert-Butylhydroperoxide Carbonyl Cyanide m-Chlorophenyl Hydrazone Cell Respiration
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Hepatoprotective Activity of Water Extracts from Chaga Medicinal Mushroom, Inonotus obliquus (Higher Basidiomycetes) Against Tert-Butyl Hydroperoxide-Induced Oxidative Liver Injury in Primary Cultured Rat Hepatocytes.

International journal of medicinal mushrooms Jan 1, 2015
We examined the hepatoprotective activity of Inonotus obliquus water extract (IO-W) against tert-butyl hydroperoxide (t-BHP)-induced oxidative liver injury in the primary cultured rat hepatocyte. The 50% radical scavenging concentrations (SC50s) of I...
Humans Cells, Cultured Animals Oxidative Stress Plant Extracts Rats Malondialdehyde Rats, Sprague-Dawley Protective Agents Hepatocytes Lipid Peroxidation Alanine Transaminase Glutathione Basidiomycota Chemical and Drug Induced Liver Injury tert-Butylhydroperoxide
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