A novel and simple electrochemical immunoassay for C-reactive protein was developed using metal-organic frameworks (Au-MOFs) as signal unit. In this study, we found MOFs could be used as signal probe. And this new class of signal probe differs from t...
Understanding the processes of mitochondrial dynamics (fission, fusion, biogenesis, and mitophagy) has been hampered by the lack of automated, deterministic methods to measure mitochondrial morphology from microscopic images. A method to quantify mit...
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
26159661
We modified a commercially available synthesis module for nucleophilic [(18)F]fluorinations (TRACERlab(TM) FXFDG, GE Healthcare) to enable the reliable synthesis of 2-[(18)F]fluoro-4-borono-L-phenylalanine ([(18)F]FBPA) via direct electrophilic subst...
Journal of chemical information and modeling
28938072
Nanoparticles exhibit diverse structural and morphological features that are often interconnected, making the correlation of structure/property relationships challenging. In this study a multi-structure/single-property relationship of silver nanopart...
First-principles calculations of charge transfer in DNA molecules are computationally expensive given that conducting charge carriers interact with intra- and intermolecular atomic motion. Screening sequences, for example, to identify excellent elect...
BACKGROUND: Electron transport chain is a series of protein complexes embedded in the process of cellular respiration, which is an important process to transfer electrons and other macromolecules throughout the cell. It is also the major process to e...
The journal of physical chemistry letters
34672582
Diabatization of one-electron states in flexible molecular aggregates is a great challenge due to the presence of surface crossings between molecular orbital (MO) levels and the complex interaction between MOs of neighboring molecules. In this work, ...
IEEE/ACM transactions on computational biology and bioinformatics
31380767
Flavin mono-nucleotides (FMNs) are cofactors that hold responsibility for carrying and transferring electrons in the electron transport chain stage of cellular respiration. Without being facilitated by FMNs, energy production is stagnant due to the i...
Chemicals can induce adverse effects in humans by inhibiting mitochondrial electron transport chain (ETC) such as disrupting mitochondrial membrane potential, enhancing oxidative stress and causing some diseases. Thus, identifying ETC inhibitors (ETC...