AIMC Topic: Translocation, Genetic

Clear Filters Showing 1 to 2 of 2 articles

Artificial intelligence to detect MYC translocation in slides of diffuse large B-cell lymphoma.

Virchows Archiv : an international journal of pathology Sep 26, 2020
In patients with suspected lymphoma, the tissue biopsy provides lymphoma confirmation, classification, and prognostic factors, including genetic changes. We developed a deep learning algorithm to detect MYC rearrangement in scanned histological slide...
Humans Phenotype Reproducibility of Results Biomarkers, Tumor Lymphoma, Large B-Cell, Diffuse Deep Learning Genetic Predisposition to Disease Staining and Labeling Predictive Value of Tests Microscopy In Situ Hybridization, Fluorescence Image Interpretation, Computer-Assisted Immunohistochemistry Proof of Concept Study Antigens, CD20 Proto-Oncogene Proteins c-myc Translocation, Genetic
View on PubMed DOI

Machine learning integrates genomic signatures for subclassification beyond primary and secondary acute myeloid leukemia.

Blood Nov 11, 2021
Although genomic alterations drive the pathogenesis of acute myeloid leukemia (AML), traditional classifications are largely based on morphology, and prototypic genetic founder lesions define only a small proportion of AML patients. The historical su...
Humans Machine Learning Leukemia, Myeloid, Acute Genomics Bayes Theorem Mutation Neoplasms, Second Primary Gene Expression Regulation, Leukemic Translocation, Genetic Cytogenetics
View on PubMed DOI
Popular Topics
Recent Journals