AIMC Topic: United States

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On the Best Way to Cluster NCI-60 Molecules.

Biomolecules Mar 8, 2023
Machine learning-based models have been widely used in the early drug-design pipeline. To validate these models, cross-validation strategies have been employed, including those using clustering of molecules in terms of their chemical structures. Howe...
Machine Learning United States Cluster Analysis National Cancer Institute (U.S.) Algorithms Drug Design
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Bayesian Statistics for Medical Devices: Progress Since 2010.

Therapeutic innovation & regulatory science Mar 3, 2023
The use of Bayesian statistics to support regulatory evaluation of medical devices began in the late 1990s. We review the literature, focusing on recent developments of Bayesian methods, including hierarchical modeling of studies and subgroups, borro...
Humans Artificial Intelligence Sample Size Bayes Theorem United States Food and Drug Administration Research Design Child United States
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An Unsupervised Machine Learning Approach to Evaluating the Association of Symptom Clusters With Adverse Outcomes Among Older Adults With Advanced Cancer: A Secondary Analysis of a Randomized Clinical Trial.

JAMA network open Mar 1, 2023
IMPORTANCE: Older adults with advanced cancer who have high pretreatment symptom severity often experience adverse events during cancer treatments. Unsupervised machine learning may help stratify patients into different risk groups.
Patient Reported Outcome Measures Unsupervised Machine Learning Humans Syndrome Female Male Aged Neoplasms United States
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Robot-related fatalities at work in the United States, 1992-2017.

American journal of industrial medicine Feb 27, 2023
BACKGROUND: Industrial robots became more commonplace in the US workplace during the mid- to latter part of the twentieth century. Recent scientific advances have led to the development of new types of robots, resulting in rapidly changing work envir...
Humans Female Adult Male Public Health Robotics Workplace Occupational Injuries Accidents, Occupational United States
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Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling.

Science robotics Feb 22, 2023
Aortic stenosis (AS) affects about 1.5 million people in the United States and is associated with a 5-year survival rate of 20% if untreated. In these patients, aortic valve replacement is performed to restore adequate hemodynamics and alleviate symp...
Robotics Ventricular Remodeling Hydrodynamics Transcatheter Aortic Valve Replacement United States Treatment Outcome Aortic Valve Stenosis Humans
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Incorporating variant frequencies data into short-term forecasting for COVID-19 cases and deaths in the USA: a deep learning approach.

EBioMedicine Feb 21, 2023
BACKGROUND: Since the US reported its first COVID-19 case on January 21, 2020, the science community has been applying various techniques to forecast incident cases and deaths. To date, providing an accurate and robust forecast at a high spatial reso...
Benchmarking Humans COVID-19 Forecasting SARS-CoV-2 Deep Learning United States
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Artificial intelligence and high-dimensional technologies in the theragnosis of systemic lupus erythematosus.

The Lancet. Rheumatology Feb 20, 2023
Systemic lupus erythematosus is a complex, systemic autoimmune disease characterised by immune dysregulation. Pathogenesis is multifactorial, contributing to clinical heterogeneity and posing challenges for diagnosis and treatment. Although strides i...
Gene Expression Profiling Genomics Epigenomics Humans Artificial Intelligence United States Lupus Erythematosus, Systemic
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Advanced-stage tongue squamous cell carcinoma: a machine learning model for risk stratification and treatment planning.

Acta oto-laryngologica Feb 15, 2023
BACKGROUND: A significant number of tongue squamous cell carcinoma (TSCC) patients are diagnosed at late stage.
Carcinoma, Squamous Cell Risk Assessment United States Databases, Factual Computer Simulation Tongue Chemoradiotherapy Neoplasm Staging Tongue Neoplasms SEER Program Humans Machine Learning
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Readmissions after radical nephrectomy in a national cohort.

Scandinavian journal of urology Jan 16, 2023
OBJECTIVE: To analyze the factors and costs associated with 30-day readmissions for patients undergoing radical nephrectomy.
Humans Postoperative Complications Patient Readmission Databases, Factual United States Hospitalization Nephrectomy Retrospective Studies Robotics Adult Risk Factors
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Abdominal and robotic sacrocolpopexy costs following implementation of enhanced recovery after surgery.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Jan 9, 2023
OBJECTIVE: To compare perioperative costs and morbidity between open and robotic sacrocolpopexy after implementation of enhanced recovery after surgery (ERAS) pathway.
Enhanced Recovery After Surgery Robotics Robotic Surgical Procedures Medicare Length of Stay United States Retrospective Studies Aged Humans Postoperative Complications
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