BACKGROUND: Isolated pancreatic metastasis from melanoma is extremely uncommon and accounts for approximately only 2% of visceral disseminations of melanoma. Interestingly, pancreatic localizations disproportionately derive from primary ocular melano...
PURPOSE: To assess the performance of machine learning (ML)-based magnetic resonance imaging (MRI) radiomics analysis for discriminating between uveal melanoma (UM) and other intraocular masses.
BACKGROUND: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Monosomy 3 and mutation are strong prognostic factors predicting metastatic risk in UM. Nuclear BAP1 (nBAP1) expression is a close immunohistochemical surro...
International journal of radiation oncology, biology, physics
Nov 15, 2025
PURPOSE: For ocular melanoma, selecting between stereotactic radiation therapy (SRT) and protons requires a lengthy plan comparison process. The purpose of this brief report is to describe an artificial intelligence (AI) decision-making tool to predi...
Uveal melanoma (UVM) is the most common primary intraocular human malignancy with a high mortality rate. Aberrant DNA methylation has rapidly emerged as a diagnostic and prognostic signature in many cancers. However, such DNA methylation signature av...
OBJECTIVE: Prognosis of patients with metastatic melanoma has dramatically improved over recent years because of the advent of antibodies targeting programmed cell death protein-1 (PD1). However, the response rate is ~40% and baseline biomarkers for ...
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