AIMC Topic: Vaccination

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An inactivated influenza D virus vaccine partially protects cattle from respiratory disease caused by homologous challenge.

Veterinary microbiology
Originally isolated from swine, the proposed influenza D virus has since been shown to be common in cattle. Inoculation of IDV to naïve calves resulted in mild respiratory disease histologically characterized by tracheitis. As several studies have as...

Large language models for analyzing open text in global health surveys: why children are not accessing vaccine services in the Democratic Republic of the Congo.

International health
BACKGROUND: This study evaluates the use of large language models (LLMs) to analyze free-text responses from large-scale global health surveys, using data from the Enquête de Couverture Vaccinale (ECV) household coverage surveys from 2020, 2021, 2022...

An informed deep learning model of the Omicron wave and the impact of vaccination.

Computers in biology and medicine
The Omicron (B.1.1.529) variant of SARS-CoV-2 emerged in November 2021 and has since evolved into multiple lineages. Understanding its transmission, vaccine efficacy, and potential for reinfection is crucial. This study examines the dynamics of Omicr...

An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study.

Science translational medicine
There are currently no licensed vaccines for norovirus, a leading cause of epidemic and endemic gastroenteritis worldwide. Clinical advancement of promising vaccine candidates from phase 2 studies to phase 3 field trials has been hampered by the lack...

TWINVAX: conceptual model of a digital twin for immunisation services in primary health care.

Frontiers in public health
INTRODUCTION: This paper presents a proposal for the modelling and reference architecture of a digital twin for immunisation services in primary health care centres. The system leverages Industry 4.0 concepts and technologies, such as the Internet of...

Modeling protective meningococcal antibody responses and factors influencing antibody persistence following vaccination with MenAfriVac using machine learning.

PloS one
Meningococcal meningitis poses a significant public health burden in the meningitis belt region of sub-Saharan Africa. The introduction of the meningococcal PsA-TT vaccine (MenAfriVac®) has successfully eliminated Neisseria meningitidis serogroup A (...

Vaccination hesitancy: agreement between WHO and ChatGPT-4.0 or Gemini Advanced.

Annali di igiene : medicina preventiva e di comunita
BACKGROUND: An increasing number of individuals use online Artificial Intelligence (AI) - based chatbots to retrieve information on health-related topics. This study aims to evaluate the accuracy in answering vaccine-related answers of the currently ...

Analyzing factors of daily travel distances in Japan during the COVID-19 pandemic.

Mathematical biosciences and engineering : MBE
The global impact of the COVID-19 pandemic is widely recognized as a significant concern, with human flow playing a crucial role in its propagation. Consequently, recent research has focused on identifying and analyzing factors that can effectively r...

Predictive overfitting in immunological applications: Pitfalls and solutions.

Human vaccines & immunotherapeutics
Overfitting describes the phenomenon where a highly predictive model on the training data generalizes poorly to future observations. It is a common concern when applying machine learning techniques to contemporary medical applications, such as predic...

Reinforcement learning relieves the vaccination dilemma.

Chaos (Woodbury, N.Y.)
The main goal of this paper is to study how a decision-making rule for vaccination can affect epidemic spreading by exploiting the Bush-Mosteller (BM) model, one of the methodologies in reinforcement learning in artificial intelligence (AI), which ca...