AIMC Topic: Viscosity

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The effect of aspect ratio on the leading-edge vortex over an insect-like flapping wing.

Bioinspiration & biomimetics
Insect wing shapes are diverse and a renowned source of inspiration for the new generation of autonomous flapping vehicles, yet the aerodynamic consequences of varying geometry is not well understood. One of the most defining and aerodynamically sign...

Effects of non-uniform stiffness on the swimming performance of a passively-flexing, fish-like foil model.

Bioinspiration & biomimetics
Simple mechanical models emulating fish have been used recently to enable targeted study of individual factors contributing to swimming locomotion without the confounding complexity of the whole fish body. Yet, unlike these uniform models, the fish b...

Time-Varying Ankle Mechanical Impedance During Human Locomotion.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
In human locomotion, we continuously modulate joint mechanical impedance of the lower limb (hip, knee, and ankle) either voluntarily or reflexively to accommodate environmental changes and maintain stable interaction. Ankle mechanical impedance plays...

A machine learning model exploring creep performance of dental composites.

Dental materials : official publication of the Academy of Dental Materials
OBJECTIVES: Viscoelastic creep behaviour of RBCs determines their dimensional stability and thus contributes to their clinical performance. However, due to complex material compositional variations and differing testing protocols, comparing and analy...

Force and torque-free helical tail robot to study low Reynolds number micro-organism swimming.

The Review of scientific instruments
Helical propulsion is used by many micro-organisms to swim in viscous-dominated environments. Their swimming dynamics are relatively well understood, but a detailed study of the flow fields is still needed to understand wall effects and hydrodynamic ...

Machine learning prediction of antibody aggregation and viscosity for high concentration formulation development of protein therapeutics.

mAbs
Machine learning has been recently used to predict therapeutic antibody aggregation rates and viscosity at high concentrations (150 mg/ml). These works focused on commercially available antibodies, which may have been optimized for stability. In this...

Calculation of therapeutic antibody viscosity with coarse-grained models, hydrodynamic calculations and machine learning-based parameters.

mAbs
High viscosity presents a challenge for manufacturing and drug delivery of therapeutic antibodies. The viscosity is determined by protein-protein interactions among many antibodies. Molecular simulation is a promising method to study protein-protein ...

Optimized Design of a Variable Viscosity Link for Robotic AFO.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Herein we present the development of a novel Ankle Foot Orthosis for gait support of people with foot-drop symptoms. The developed AFO uses an elastic link mechanism to brake the ankle joint during initial contact, thus mitigating foot-slap, and an i...

A biorobotic model of the human larynx.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
This work focuses on a physical model of the human larynx that replicates its main components and functions. The prototype reproduces the multilayer vocal folds and the ab/adduction movements. In particular, the vocal folds prototype is made with sof...