Central nervous system (CNS) involvement in primary Sjögren's syndrome (pSS), although less frequent, can lead to serious complications. Our study aimed to assess white matter (WM) tract integrity, identify specific regions of disruption, quantify di...
BACKGROUND: Maximal tumor resection with neurological preservation is central to brain tumor surgery. This study evaluates the integration of an artificial intelligence-based connectomics platform for surgical planning, with exploratory tractometry a...
Biomechanics and modeling in mechanobiology
Dec 12, 2025
Large-scale axonal dynamic simulation is critical to study white matter injury but is prohibitive in computational cost. We solve this challenge by training a convolutional neural network (CNN) that takes fiber strain profiles as inputs to instantly ...
Biomedical physics & engineering express
Dec 4, 2025
Leukodystrophies are a group of inherited disorders that predominantly and selectively affect the white matter of the central nervous system. Their overlapping clinical and imaging manifestations make a timely and accurate diagnosis challenging. In t...
We developed and validated an artificial intelligence (AI) algorithm for the automated grading of periventricular hyperintensity (PVH) and deep subcortical white matter hyperintensity (DWMH) using magnetic resonance imaging. Overall, 246 patients wer...
To quantitatively measure the volume of white matter hyperintensities (WMHs) in different parts of the brain in patients with different types of cognitive function and analyze the relationship between WMH volume and cognitive function to obtain a thr...
Traditional brain connectivity studies have focused mainly on structural connectivity, often relying on tractography with diffusion MRI (dMRI) to reconstruct white matter pathways. In parallel, studies of functional connectivity have examined correla...
Neuroimaging studies of brain function are important research methods widely applied to stroke patients. Currently, a large number of studies have focused on functional imaging of the gray matter cortex. Relevant research indicates that certain areas...
BACKGROUND: Fetal diffusion-weighted Magnetic Resonance Imaging (dMRI) represents a promising modality for the assessment of white matter fiber organization, microstructure and development during pregnancy. Over the past two decades, research using t...
BACKGROUND: Identifying key areas of brain dysfunction in mental illness is critical for developing precision diagnosis and treatment. This study aimed to develop region-specific brain aging trajectory prediction models using multimodal magnetic reso...
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